Protein Alignment CSNK1A1 and CG12147

DIOPT Version :10

• Sequence 1: NP_001020276.1
• Gene: CSNK1A1 / 1452
• HGNCID: 2451
• Length: 365
• Species: Homo sapiens
• Sequence 2: NP_649536.1
• Gene: CG12147 / 40651
• FlyBaseID: FBgn0037325
• Length: 477
• Species: Drosophila melanogaster
• Alignment Length: 357
• Identity: 177/357 - (49%)
• Similarity: 242/357 - (67%)
• Gaps: 33/357 - (9%)

Human     7 SKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGV 71
            |..|.||.|||:|:::||:||||:::.|..:...|:||:||||...:||.|..|:::|.|||||:
  Fly    58 SLPEIIVAGKYRLLKRIGNGSFGELFQAEGLKYHEKVAIKLESSTVKHPLLPREARIYGILQGGL 122

Human    72 GIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRD 136
            ||||::.|..|..|||:|||||||:||||.|.|||.|:|||.||||||:::|:|.:|.:.|||||
  Fly   123 GIPHVKHYATEGAYNVMVMDLLGPTLEDLLNLCSRSFSMKTTLMLADQILARVELLHRRCFIHRD 187

Human   137 IKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLNQLFLIDFGLAKKYRDNRTRQHI 201
            |||||||||:.||                            ..|:::||||||||:...||::||
  Fly   188 IKPDNFLMGLNRH----------------------------QTQVYMIDFGLAKKFYSLRTQKHI 224

Human   202 PYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISE 266
            .|.|:::|.|||||||:.||.. |||||||:||:||:|:||.|..|||||::|.::.||||||:|
  Fly   225 GYTENRDLVGTARYASVRAHYA-EQSRRDDLESVGYLLLYFQRGRLPWQGIRAQSQAQKYEKIAE 288

Human   267 KKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQ 331
            .|.:.|::.||.|.|.||.|||.|||.|.|.|.|||:||:|||::|||......|:.|||.:||:
  Fly   289 YKANIPLQQLCSGLPVEFFMYLKYCRKLHFAEKPDYVYLQQLFKVLFRNQYKVCDFLFDWVVLKR 353

Human   332 KAAQQAASSSG----QGQQAQTPTGKQTDKTK 359
            ::.:|.:...|    :|.:......|:..:.|
  Fly   354 ESPEQQSQQKGRERDRGGKRNVVVQKERHRNK 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK1A1	NP_001020276.1	STKc_CK1_alpha	16..309	CDD:271030	156/292 (53%)
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	156/292 (53%)