Protein Alignment Gata6 and grn

DIOPT Version :9

• Sequence 1: XP_017173323.1
• Gene: Gata6 / 14465
• MGIID: 107516
• Length: 590
• Species: Mus musculus
• Sequence 2: NP_001262366.1
• Gene: grn / 40962
• FlyBaseID: FBgn0001138
• Length: 712
• Species: Drosophila melanogaster
• Alignment Length: 700
• Identity: 217/700 - (31%)
• Similarity: 282/700 - (40%)
• Gaps: 194/700 - (27%)

Mouse     5 DGGWCLPKRFGAAAADAGDSGPFPAREPSSPLSPISSSSSSCSRGGDRGPCGASNCRTPQLDAEA 69
            :||...|:..|     .|.:|...|....|..|..||:.||...|...|..|.|...|..:.|..
  Fly    30 NGGGVSPQTNG-----LGSAGSSLAHSHHSLSSGASSAGSSVGVGSALGGGGGSGLDTSDMSAFY 89

Mouse    70 VAGPPGRSLLLSP-YASHPFAAAHGAAAPGVAGP--GSALSTWEDLLLFTDLDQAATASKLLWSS 131
            .....|......| |..|........|:|.|..|  .:.||.|    |.::....|.||  .||
  Fly    90 ALESNGHHRRYYPSYHQHTSRMPSTHASPQVCRPHFHTPLSPW----LTSEHKSFAPAS--AWS- 147

Mouse   132 RGAKLSPFAAEQPEEM----------YQTLAA------------------LSSQGPAAYDGAPGG 168
                :..||..|..::          :||.||                  ....||:.|......
  Fly   148 ----MGQFACPQEPQVEHKLGQMGQSHQTTAAGQHSFPFPPTPPKDSTPDSVQTGPSEYQAVMNA 208

Mouse   169 FVHSAAAAAAAAAAASSPVYV-PTTRVGSMLSGLPYLQGAGSG------PSNHAGGAGAHPGWS- 225
            |:|..|..:.:...||..:.: |:.:.|| .||     .:|||      |....|.|......|
  Fly   209 FMHQQATGSTSLTDASCALDIKPSIQNGS-ASG-----SSGSGTTHTSTPKQREGTASTTNSSSN 267

Mouse   226 -------------------QASADSPPYGGGGAAGGGAAGPGGAGSATAHASARFPYSPSPPMAN 271
                               |:|:::.......|:...||....|..|.:.|::          :|
  Fly   268 SSSSQQQQQQQQQQQQQQQQSSSNTTASSNTSASSSAAAASLSAAVAASAATS----------SN 322

Mouse   272 GAARDPGGYVAAGGTGAGSVSGGGGSLAAMGGRE-------------HQYSSLSAARPLNGT--- 320
            |.........::||:|.|   |||||  ..||.:             ||.::::||.....:
  Fly   323 GLFDGTAQAYSSGGSGGG---GGGGS--GSGGYDTSSYASYHHAAAHHQAAAVAAANMFQSSSVA 382

Mouse   321 -------------YHHHHHHHPTY------------------SPYMAAPLTPAWPAGPFETPVLH 354
                         :|||||||..:                  :..|.:....:..||
  Fly   383 AAAVRHSMAAAQAHHHHHHHHSGHHHSGSSSGLHGLGGSVGGTAGMGSMSGNSGGAG-------- 439

Mouse   355 SLQGRAGA----------PLPVPRGPSTDLLEDLSESRECVNCGSIQTPLWRRDGTGHYLCNACG 409
            ||.|.:||          ..||...|.|.     :|.|||||||:..||||||||||||||||||
  Fly   440 SLSGHSGAGSNAGSNCLDVKPVRTKPRTS-----AEGRECVNCGATSTPLWRRDGTGHYLCNACG 499

Mouse   410 LYSKMNGLSRPLIKPQKRV------PSSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKL 468
            ||.||||.:||||||::|:      .:::|.|.|||||.|||||||||||.|||||||||||.||
  Fly   500 LYYKMNGQNRPLIKPKRRLTLQSLQSAAKRAGTSCANCKTTTTTLWRRNASGEPVCNACGLYYKL 564

Mouse   469 HGVPRPLAMKKEGIQTRKRKPKNINKSKACSGNSSGSVPMTPTSSSSNSDDCTKNTSPSTQATTS 533
            |.|.|||.|||||||||.||..  :|||...|...|.:|:.......:    .|...||...
  Fly   565 HNVNRPLTMKKEGIQTRNRKLS--SKSKKKKGLGGGCLPIGGHLGMGD----FKPLDPSKGF--- 620

Mouse   534 GKPGDSFVESASQY------LDPLAHPCLLLSW-RGGLTAAPVTGSGRGI 576
               |..|..|.:|:      |.| ||..:..|| .||:.|   .|:..|:
  Fly   621 ---GGGFSASMAQHGHLSSGLHP-AHAHMHGSWYTGGMGA---LGASSGL 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gata6	XP_017173323.1	GATA-N	147..371	CDD:368398	66/335 (20%)
		ZnF_GATA	383..428	CDD:238123	36/44 (82%)
		ZnF_GATA	437..488	CDD:238123	43/50 (86%)
grn	NP_001262366.1	ZnF_GATA	470..517	CDD:214648	38/46 (83%)
		ZnF_GATA	473..517	CDD:238123	36/43 (84%)
		ZnF_GATA	529..578	CDD:214648	40/48 (83%)
		ZnF_GATA	533..583	CDD:238123	43/49 (88%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1745
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840