Protein Alignment Gata4 and grn

DIOPT Version :10

• Sequence 1: NP_001297539.1
• Gene: Gata4 / 14463
• MGIID: 95664
• Length: 442
• Species: Mus musculus
• Sequence 2: NP_001262366.1
• Gene: grn / 40962
• FlyBaseID: FBgn0001138
• Length: 712
• Species: Drosophila melanogaster
• Alignment Length: 507
• Identity: 177/507 - (34%)
• Similarity: 222/507 - (43%)
• Gaps: 132/507 - (26%)

Mouse    15 PGAYEAGGPGAFMHSAGAASSPVYVPTPRVPSSVLGLS-YLQGGGSAAAAGT------------- 65
            |..|:| ...||||.....|:.:     ...|..|.:. .:|.|.::.::|:
  Fly   199 PSEYQA-VMNAFMHQQATGSTSL-----TDASCALDIKPSIQNGSASGSSGSGTTHTSTPKQREG 257

Mouse    66 TSGGSSGAGPSGAGPGTQQGSPGWSQAGAEGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAARE-- 128
            |:..::.:..|.:....||......|...:.::.|....:...|......||:||.||:||..
  Fly   258 TASTTNSSSNSSSSQQQQQQQQQQQQQQQQSSSNTTASSNTSASSSAAAASLSAAVAASAATSSN 322

Mouse   129 ------AAAYGSGGGAAGAGLAGREQYGRPGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDSP 187
                  |.||.|||...|.|       |..|..|..:|.|.:| ....|...|||.|:|..|.|.
  Fly   323 GLFDGTAQAYSSGGSGGGGG-------GGSGSGGYDTSSYASY-HHAAAHHQAAAVAAANMFQSS 379

Mouse   188 V----------------------------------LH-----------------------SLPGR 195
            .                                  ||                       ||.|.
  Fly   380 SVAAAAVRHSMAAAQAHHHHHHHHSGHHHSGSSSGLHGLGGSVGGTAGMGSMSGNSGGAGSLSGH 444

Mouse   196 ANPGRH--PNLVDMFD------DFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINR 252
            :..|.:  .|.:|:..      ..:||||||||||.|||||||||||||||||||||:||||.||
  Fly   445 SGAGSNAGSNCLDVKPVRTKPRTSAEGRECVNCGATSTPLWRRDGTGHYLCNACGLYYKMNGQNR 509

Mouse   253 PLIKPQRRL------SASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMR 311
            |||||:|||      ||::|.|.|||||:|||||||||||.|||||||||||.|||.|.|||.|:
  Fly   510 PLIKPKRRLTLQSLQSAAKRAGTSCANCKTTTTTLWRRNASGEPVCNACGLYYKLHNVNRPLTMK 574

Mouse   312 KEGIQTRKRKPKNLNKSKTPAG----PAG--------ETLPPSSGASSGNSSNATSSSSSSEEMR 364
            |||||||.||..:.:|.|...|    |.|        :.|.||.|...|.|::.......|..:.
  Fly   575 KEGIQTRNRKLSSKSKKKKGLGGGCLPIGGHLGMGDFKPLDPSKGFGGGFSASMAQHGHLSSGLH 639

Mouse   365 PIKTE------PGLSSHYGHSSSMSQTFST---VSG----HGPSIHPVLSAL 403
            |....      .|.....|.||.:...|||   :||    |....|..||::
  Fly   640 PAHAHMHGSWYTGGMGALGASSGLQGGFSTAGSLSGAVVPHSQPYHLGLSSM 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gata4	NP_001297539.1	GATA-N	1..204	CDD:461628	56/269 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..107		7/59 (12%)
		ZnF_GATA	216..266	CDD:238123	44/55 (80%)
		ZnF_GATA	270..321	CDD:238123	42/50 (84%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	314..393		29/103 (28%)
grn	NP_001262366.1	ZnF_GATA	473..517	CDD:238123	39/43 (91%)
		ZnF_GATA	533..583	CDD:238123	42/49 (86%)