Protein Alignment CG43968 and ADGRG7

DIOPT Version :9

• Sequence 1: NP_001262238.1
• Gene: CG43968 / 14462915
• FlyBaseID: FBgn0264699
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_116176.2
• Gene: ADGRG7 / 84873
• HGNCID: 19241
• Length: 797
• Species: Homo sapiens
• Alignment Length: 569
• Identity: 108/569 - (18%)
• Similarity: 186/569 - (32%)
• Gaps: 190/569 - (33%)

  Fly   299 FFIHHSTKMEYVIKMSLSEDFQIVSKGLKWIPTLSKQIVKS---------SSAVEMVLEIDHRSK 354
            |.::.:.|:......:...||             |::|:.|         |::|:||....:..|
Human   323 FVVYQNDKLFQSKTFTAKSDF-------------SQKIISSKTDENEQDQSASVDMVFSPKYNQK 374

  Fly   355 GVRLVIYNRKYLW---------------KNNNSYVGVKCFALLKYGTLKNVRLDLIWENQEQSYS 404
            ..:|..|...| |               |..:.::..:|.....:..|...:.|         |.
Human   375 EFQLYSYACVY-WNLSAKDWDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKD---------YQ 429

  Fly   405 ILK-VNIVSSYRTEYWCEGHSIFEFQLVSTRLFVDVNRSIAPVFVLRWNVSCINANFAYNLCDEV 468
            ..| ::|:|:.       |.::....|..|.:|..|.|.:....| .|        ...|||..:
Human   430 YPKSLDILSNV-------GCALSVTGLALTVIFQIVTRKVRKTSV-TW--------VLVNLCISM 478

  Fly   469 TDKNLRKLIESVYG-NNNLGNLLIYDVRIMNIEWIKN-------------MCVV------FWIHI 513
            ...||.    .|:| .|:..||...|..|.||::..|             ||..      :::.:
Human   479 LIFNLL----FVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLV 539

  Fly   514 TATLK--STASTYHKEIAFVDNTPRIPKDFVAFMK----------VKITLSNFFLNFIKNSTYLL 566
            |.|..  |.|..|:   ..:.....:|:.|:.|:.          |.||:...:.....|..:.|
Human   540 TFTWNALSAAQLYY---LLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWEL 601

  Fly   567 --RSTDYCFSELSFSNDGMH--LWW------TTTRIGEIAMTKKLCIQKDGMPYTRLCLGDFVHG 621
              |....|:..:...|..:.  |.|      |...|..:.|...:.|:
Human   602 DYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIK----------------- 649

  Fly   622 AYWK---KLTQPVVCESPKNNTKVLHDLQVAKMFKSPPEKVLKYLKDIIANSKNSIVPADIFLIY 683
            ..||   .||......|.|   |::..|.||.:|..  ..:|.||. ::.:....||.:.||.::
Human   650 VLWKNNQNLTSTKKVSSMK---KIVSTLSVAVVFGI--TWILAYLM-LVNDDSIRIVFSYIFCLF 708

  Fly   684 KIFQSVHEIHSSNSEFQQTTKDLTNWKNAIYEIFDIYNVLIGL----DSKVIKMSAELNATNM-- 742
                             .||:.|        :||.:|.|...:    .|||:.:.:.:.....
Human   709 -----------------NTTQGL--------QIFILYTVRTKVFQSEASKVLMLLSSIGRRKSLP 748

  Fly   743 -------------FLKS-------FEMLFDTLSLNNLSFTQIDNGEEHL 771
                         ||:|       |.:|..:.|...::.::.||.:|.:
Human   749 SVTRPRLRVKMYNFLRSLPTLHERFRLLETSPSTEEITLSESDNAKESI 797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43968	NP_001262238.1	None
ADGRG7	NP_116176.2	GPS	383..422	CDD:197639	4/39 (10%)
		7tmB2_GPR128	431..737	CDD:320385	78/376 (21%)
		TM helix 1	433..458	CDD:320385	6/31 (19%)
		TM helix 2	468..490	CDD:320385	8/33 (24%)
		TM helix 3	527..554	CDD:320385	5/29 (17%)
		TM helix 4	567..587	CDD:320385	4/19 (21%)
		TM helix 5	621..651	CDD:320385	6/46 (13%)
		TM helix 6	665..692	CDD:320385	10/32 (31%)
		TM helix 7	699..724	CDD:320385	11/49 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810