DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43968 and Adgrf1

DIOPT Version :9

Sequence 1:	NP_001262238.1	Gene:	CG43968 / 14462915	FlyBaseID:	FBgn0264699	Length:	1026	Species:	Drosophila melanogaster
Sequence 2:	XP_006525183.1	Gene:	Adgrf1 / 77596	MGIID:	1924846	Length:	927	Species:	Mus musculus

Alignment Length:	335	Identity:	60/335 - (17%)
Similarity:	114/335 - (34%)	Gaps:	87/335 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 TINNQTPADFKSQIVSVDCNAFLNAVCIFKSELISNAGCPSGFGALVYQPAVCYGIDWNNTTYEP 265
            ||..|...|..||::..     |.::    |.||.:...|..|....        |||..|   |
Mouse   409 TILLQDAKDASSQLLKT-----LESI----SSLIPSMALPLNFSGKF--------IDWKGT---P 453

  Fly   266 LDLKEYLKKRNWLRRILAKYVLKKNRHEFFKID-FFIHHSTKMEYVIKMSLSEDFQIVSKGLKWI 329
            :...:..:..|:...:.....|....|.|.:.| |...|...:..:..::..:...|..:|..|:
Mouse   454 VTQIQSTRGYNYQMEMRQNASLPIRGHVFIEPDQFQKSHPKTIISMASLTFGDILPITQRGNAWV 518

  Fly   330 --PTLSKQIVKSSSAVEMVLEIDHRSKGVRLVIYNRKYLWKNNNSYVGVKCFALLKYGTLKNVRL 392
              |.:| .::::.|..|:.|.                              |:.:| |.|...|.
Mouse   519 NGPVIS-TLIQNYSISEIFLN------------------------------FSKIK-GNLTQPRC 551

  Fly   393 DLIWENQEQSYSILKVNIVSSYRTEYWCEGHSIFEFQLVSTRLFVDVNRSIAPVFVLRWNVSCIN 457
             :.|:..:..:|.....:|:.......|....:..|.::.:..   |..|:.|  |::| ::.|.
Mouse   552 -VFWDFSQLQWSNAGCQLVNETLDTVLCRCSHLTSFSMLMSPF---VPSSVVP--VVKW-ITYIG 609

  Fly   458 ANFAYNLCDEVTDKNLRKLIESVYGNNNLGNLLIYDVRIMNIEWIKNMCVV----------FWIH 512
            .:.:      :....|..:|||::..         ..:.....:.:|:|:|          .|..
Mouse   610 LSIS------IASLILCLIIESLFWK---------QTKRSQTSYTRNICLVNIAVSLLIADVWFI 659

  Fly   513 ITATLKSTAS 522
            |.||:..:.|
Mouse   660 IAATVDPSVS 669

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43968	NP_001262238.1	None
Adgrf1	XP_006525183.1	SEA	172..258	CDD:366610
		GPS	549..590	CDD:197639	6/41 (15%)
		7tm_GPCRs	603..866	CDD:391938	14/83 (17%)
		TM helix 1	603..626	CDD:341315	5/29 (17%)
		TM helix 2	641..663	CDD:341315	5/21 (24%)
		TM helix 3	675..702	CDD:341315
		TM helix 4	716..736	CDD:341315
		TM helix 5	757..786	CDD:341315
		TM helix 6	803..829	CDD:341315
		TM helix 7	834..859	CDD:341315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900