Protein Alignment CG43968 and adgrl1a

DIOPT Version :9

• Sequence 1: NP_001262238.1
• Gene: CG43968 / 14462915
• FlyBaseID: FBgn0264699
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: XP_021330394.1
• Gene: adgrl1a / 562531
• ZFINID: ZDB-GENE-131127-267
• Length: 1524
• Species: Danio rerio
• Alignment Length: 1070
• Identity: 186/1070 - (17%)
• Similarity: 324/1070 - (30%)
• Gaps: 408/1070 - (38%)

  Fly   126 CYGSNIIAMDLQNFELSKVSQFLKKMNISDFWLPIRRNDELM---PYEVRLPGKSWRKEINRSLI 187
            |.||::|.::..|:.                    |.:|::.   |:::.
Zfish    50 CPGSDVIMIETANYG--------------------RTDDKICDADPFQME--------------- 79

  Fly   188 HLQNNPNEHCLKHTINNQTPADFKSQIVSVDCNAFLNAVCIFKSELISNAGCPSGFGALVYQ-PA 251
                  |..|       ..|..||  |:|..||.....|.:..|::..:. ||..:..|..| ..
Zfish    80 ------NVQC-------YLPDAFK--IMSQRCNNRTQCVVVAGSDVFPDP-CPGTYKYLEIQYEC 128

  Fly   252 VCYGIDWNNTTYEPLDLKEYLKKRNWLRRILAKYVLKKNRHE---FFKIDFFIHHSTKMEYVIKM 313
            |.|.:|           ::.......|.|:.|..:|::..|:   :.|...   .|....||
Zfish   129 VPYKVD-----------QKVFVCPGTLLRVQAASLLQEAEHQSGAWCKDPL---QSGDRLYV--- 176

  Fly   314 SLSEDFQIVSKGLKWIPTLSKQIVKSSS-------AVEMVLEIDHRSKGVRLVIYNRKYLWKNNN 371
                        :.|.|..:..:.:.:|       ......::.:|..|...|:|:
Zfish   177 ------------MPWTPYRTDMLYEYASWEDFKQNRATTTYKLPNRVDGTGFVVYD--------- 220

  Fly   372 SYVGVKCFALLKYGTLKNVRLDLIWENQEQSYSILKVNI------------------VSSYRTEY 418
                                 ..::.|:|::.:|:|.::                  .|.||
Zfish   221 ---------------------GAVFYNKERTRNIVKYDLRTRIKSGEAIVNNANYHDTSPYR--- 261

  Fly   419 WCEGHSIFEFQLVSTRLFV----DVNRSIAPVFVLRWNVSCINANFAYNLCDEVT-----DKNLR 474
            | .|.|..:..:....|:|    :.|..       |..||.:|   .|.|..|.|     ||.|.
Zfish   262 W-GGKSDIDLAVDENGLWVIYATEANNG-------RLVVSQVN---PYTLRFEGTWETSFDKRLA 315

  Fly   475 K----------LIESVYGNNNL---GNLLIYDVRIMNIEWIKNMCVVFWIHITATLKSTASTYHK 526
            .          .:.|||.:::.   |:|::|       .:..|......:||      .....::
Zfish   316 SNAFMACGVLYAVRSVYQDDDSEAGGDLVLY-------AYNTNRAREEPVHI------PFPNPYQ 367

  Fly   527 EIAFVDNTPRI-------------------PKDFVAFMKVKITLSNFFLNFIK--NSTYL----- 565
            .::.||..||.                   |.|..|...|...:|:......:  .||.|
Zfish   368 YVSSVDYNPRDNQLYVWNNYNVLRYPLEFGPPDPTAGPPVTTQMSSSTTTAARPITSTSLPSTIR 432

  Fly   566 -LRSTDYCFSELSFSNDGMHLWWTTTRIGEIAMTKK-LCIQKDGMPYTRLCLGDFVHGAYW---- 624
             |..|.:....::.:.|...:  |.|    :.:|:: |.:...| |...:|......|..|
Zfish   433 PLPPTAHPIGAINKAPDLRPI--TAT----VPVTRRPLRVPPQG-PEIEVCESRVARGVQWPATQ 490

  Fly   625 -------------------KKLTQPVV----------CESPKNNTKVLHDLQVAKMFKSPPEKVL 660
                               :.|:.||:          |.||..|       |||:..|| .|...
Zfish   491 KGETVDRPCPKGSLGIASFQCLSSPVLWNPRGPDLSNCTSPWVN-------QVAQKIKS-GENAA 547

  Fly   661 KYLKDIIANSKNSIVPADIFLIYKIFQSVHEI--------HSSNSEFQQTTKDLTNWK------- 710
            ....:::.:::..|...|:....::.:.:.:|        ...|.|  ...::...|:
Zfish   548 NIAAELVNHTQGRIHAGDVSSSVRLIEQLLDILDAQLQALRPGNKE--SAARNYNKWQKRERTCR 610

  Fly   711 ---NAIYEIFDIYNVLIGLDSKVIKMSAELNATNMFLKSFEMLFDTLSLNNLSFTQIDNGEEHLN 772
               .|:.:..|  |:   |.::.::...::|:|.. ..:..||.|.:.
Zfish   611 AYVQAVVQTVD--NL---LRAEALESWQDMNSTEQ-AHTATMLLDVME----------------- 652

  Fly   773 DFNSETIDYDDIGVSVYVSKYILYFSIIPSIANVSGIALFANNNKKNTPTKLKGAFKNEHYRFLQ 837
                                              .|..|.|||            ..|.|:....
Zfish   653 ----------------------------------KGAFLLANN------------MYNNHFSDHA 671

  Fly   838 VNHN-----INDVVNEPDLELAAYLPIELIDTLQAST----NKTNDVIVVIKVYSNDELFQQSV- 892
            .|.:     :|...:..||......|.:....|.|||    ::...|.||..:|.|...|..:.
Zfish   672 ANVDLEVRVLNTETDSQDLSFPQSGPSDSSIQLSASTFKQYSRNGQVKVVFVLYKNLGSFLSTEN 736

  Fly   893 -------------RNLTLLSRVVSISLPGYSS--FLPVPVPLIFRKSKNKKVNPPGSCLVWNYEG 942
                         |.|.:.|.|::.|:...||  ||..||....|..:.:....| :|..|||
Zfish   737 ATVKMEMEAGIGGRGLAVNSHVIAASINKESSRVFLTEPVVFTLRHLQLENHFSP-NCSFWNY-- 798

  Fly   943 WIDGYSMLSYFENNEGIALCRLRRLAPT------GYFLEKKISIENHIINHDLRMSNTKL----- 996
              ...||...: :::|   |||.....|      .:.....:.:.:|..::..||....|
Zfish   799 --SERSMTGQW-SSQG---CRLIETNSTHTTCSCSHLTNFAVLMVHHEPDYPGRMHELILFVITW 857

  Fly   997 NGNIIYVILLSCCILMFIGFLFCKCIFRRL 1026
            .|.:|.::.|:.||..|       |..|.|
Zfish   858 VGIVISLVCLAICISTF-------CFLRGL 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43968	NP_001262238.1	None
adgrl1a	XP_021330394.1	Gal_Lectin	48..128	CDD:307994	23/128 (18%)
		OLF	142..398	CDD:321983	53/330 (16%)
		HormR	474..535	CDD:214468	10/67 (15%)
		GAIN	545..765	CDD:318649	42/290 (14%)
		GPS	789..836	CDD:197639	12/55 (22%)
		7tmB2_Latrophilin-1	849..1106	CDD:320673	10/39 (26%)
		TM helix 1	851..876	CDD:320673	7/31 (23%)
		TM helix 2	885..907	CDD:320673
		TM helix 3	916..943	CDD:320673
		TM helix 4	955..975	CDD:320673
		TM helix 5	992..1021	CDD:320673
		TM helix 6	1037..1064	CDD:320673
		TM helix 7	1068..1093	CDD:320673
		Latrophilin	1105..1524	CDD:308136

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810