Protein Alignment CG43968 and adgrv1

DIOPT Version :9

• Sequence 1: NP_001262238.1
• Gene: CG43968 / 14462915
• FlyBaseID: FBgn0264699
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: XP_009300028.1
• Gene: adgrv1 / 415105
• ZFINID: ZDB-GENE-040624-6
• Length: 6208
• Species: Danio rerio
• Alignment Length: 975
• Identity: 169/975 - (17%)
• Similarity: 332/975 - (34%)
• Gaps: 337/975 - (34%)

  Fly    97 DDLFEIQN--VGNIPICLKISTEPKAFNEQFCYGSNIIAMDLQNFELSKVSQFLKKMNISDFWLP 159
            ||:.|:|.  :.||...:.|:|.|.|...:..|       .|::.| ..|::.:
Zfish  2897 DDIPELQEFFLVNITSAVLITTLPTAPKLKIYY-------TLKDTE-GLVAEII----------- 2942

  Fly   160 IRRNDELMPYEVRLPGKSWRKEINRSLIHLQNNPNEHCLKHTINNQTPADFKSQIVSVDCNAFLN 224
            |..||.:                 |.:|..||  .::.:..||...|...::      |...:.|
Zfish  2943 INANDGI-----------------RGIIGWQN--IDYVVNETIGVLTLVAYR------DAGTYGN 2982

  Fly   225 AVCIFKSELISNAGCPSGFGALVYQPAVCYGIDWNNTTYEPLDLKEYLKKRNWLRRILAKYVLKK 289
            ....|.::.:.                ...|:|:|.|   |..:                |.:..
Zfish  2983 VSLFFYAQNLE----------------AQLGLDFNAT---PSMI----------------YFVDG 3012

  Fly   290 NRHEFFKIDFFIHHSTKMEYVIKMSLSEDFQIVSKGLKWIPTLSKQIVKSSSAVEMVLEIDHRSK 354
            .||:|.::..       ::..:... .|.||::...    |:...|:.::::|..|:|..|   .
Zfish  3013 ERHKFIEVQI-------LDDAVPEG-DETFQLILAN----PSAGLQLGENTTATVMILAND---D 3062

  Fly   355 GVRLVIYNRK--YLWKNNNSYVGVKCFALLKY-------GTLKNVRL--------------DLIW 396
            |..::.:|..  :|.:...|..|:.......|       ||...|.:              ||
Zfish  3063 GHGIISFNNSEHFLLREPTSVSGLGTSVATLYIIRDPPQGTFGTVTVQFTITDVNGSLNTDDL-- 3125

  Fly   397 ENQEQSYSILKVNIVSSYRT-EYWC------EGHSIFEFQL----------VSTRLFVDVNRSIA 444
             .....:.:|:..:  .|:| |.|.      |.:..|...|          ||.:.|:.|..:.|
Zfish  3126 -TPSSGFVVLEDGV--RYKTLEIWAVLDAEPEMNETFTVTLSNPTGGARLGVSLQTFITVLENQA 3187

  Fly   445 PVFVLRWNVSCINANFAYNLCDEVT-DKNLRKLIESVYGNNNLGNLLIYDVRIMNIEWIKNMCVV 508
            |:.:.|.:.| ||...     |.:| ::::..:..:|..:|.|.:       .:::||.......
Zfish  3188 PLGLFRISPS-INRTL-----DTMTVEEHMGTVFLTVSRSNGLES-------AVSVEWETRSGTA 3239

  Fly   509 FWIH----ITATLKSTASTYHKEIAFVDNTPRIPKDFVAFMKVKITLSNFFLNFIK----NSTYL 565
            |.:.    :.|..:|...      :|......:|.:..|.:          |..|:    |.|.|
Zfish  3240 FGMRGEQPVLAVYQSIRD------SFASVWCSVPSEDAALV----------LRLIRGLTQNQTVL 3288

  Fly   566 LRSTDYCFSELSFSNDGMHLWWTTTRIGEIAMTKKLCIQKDGMPYTRLCLGDFVHGAYWKKLTQP 630
            .:                   |.    |.....:.:.||.     .:.|:|..|:|:.:
Zfish  3289 YK-------------------WQ----GVFVPVEFVSIQN-----PKSCVGFTVNGSSY------ 3319

  Fly   631 VVCESPKNNT----------KVLHDLQVA--KMFKSPPEKVLKYLKD----IIANSKNSIVPADI 679
             |..|..:||          :|..||.:.  :.|......|..:..|    :||:|:..:.....
Zfish  3320 -VAVSHADNTVSLTTNISLFRVQADLNLTLEQTFTVSGFSVKHFSTDLKQYLIASSEIFVWNRGS 3383

  Fly   680 FLIYKIFQSVHEI--------HSSNSEFQQTTKDLTNWKNAIYEIFD-----------------I 719
            |.:::..: :.:|        .|||.:.....::.|:....||:..|                 :
Zfish  3384 FFLHQSLE-LQDIIAAVPFRRGSSNVQHLAVCRNRTSAACFIYQWTDGRFQSPQPLALNTQVKQV 3447

  Fly   720 YNVLIGLDSKVIKMSAELN-ATNMFL-KSFEMLF-DTLSLNNLSFTQIDNGEEHLNDFNSETIDY 781
            .:..:|.|:.:..::..|| |..:|| .|.:.:| .|.|:       :..|...::.|.:.:
Zfish  3448 ESHQMGGDTFLFIVTEGLNPACEVFLWGSQQTVFQQTQSI-------LVPGLFSVHPFTTPS--- 3502

  Fly   782 DDIGVSVYVSKYILYFSIIPSIANVSGIALFANNNKKNTPTKLKGAFKNEHYRFLQVNHNINDVV 846
               |:|     ::|       :|.|:|.||:              ::::|..:|.       :::
Zfish  3503 ---GIS-----HLL-------LAGVNGSALY--------------SWRSELRQFA-------EML 3531

  Fly   847 NEPDLELAAYLPIELIDTLQA---STNKTNDVIVVIKVYSNDE---------LFQQSVRNLTLLS 899
            ..|..:...|||:..|::.::   ::.|::.::..:...||..         .||..|:.|.:..
Zfish  3532 KSPSAQEFLYLPVPSINSTKSLILASGKSSSLVYELTSVSNQSDFIPSSGELFFQPGVQELEIAV 3596

  Fly   900 RVVSISLPGYSSFLPVPVPLIFRKSKNKKVNPPGSCLVWNYEGWI--------DGYSMLSYFENN 956
            .|:...:|.....        ||.|..   ||.|...: .:.|.:        |.|.::.:.:|:
Zfish  3597 NVIDDDVPEEEEH--------FRVSLK---NPKGGAEI-GFRGQVTFFIPANDDTYGIIGFSQNS 3649

  Fly   957  956
            Zfish  3650  3649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43968	NP_001262238.1	None
adgrv1	XP_009300028.1	Calx-beta	138..230	CDD:295344
		Calx-beta	256..355	CDD:295344
		Calx-beta	766..853	CDD:295344
		Calx-beta	880..971	CDD:295344
		Calx-beta	996..1082	CDD:295344
		Laminin_G_3	1343..1484	CDD:290121
		Calx-beta	1576..1654	CDD:295344
		Calx-beta	1712..1794	CDD:295344
		Calx-beta	1849..1939	CDD:295344
		Calx-beta	1975..2065	CDD:295344
		Calx-beta	2105..2193	CDD:295344
		Calx-beta	2220..2310	CDD:295344
		Calx-beta	2590..2656	CDD:295344
		Calx-beta	2951..3039	CDD:295344	21/138 (15%)
		Calx-beta	<3574..3614	CDD:295344	8/47 (17%)
		Calx-beta	3641..3729	CDD:295344	1/9 (11%)
		Calx-beta	<3788..3864	CDD:295344
		Calx-beta	4021..4112	CDD:295344
		Calx-beta	4257..4345	CDD:295344
		Calx-beta	4390..4480	CDD:295344
		Calx-beta	5003..5085	CDD:295344
		7tm_4	<5871..>5926	CDD:304433

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900