DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43968 and Adgrg3

DIOPT Version :9

Sequence 1:	NP_001262238.1	Gene:	CG43968 / 14462915	FlyBaseID:	FBgn0264699	Length:	1026	Species:	Drosophila melanogaster
Sequence 2:	XP_038954076.1	Gene:	Adgrg3 / 291854	RGDID:	1305674	Length:	574	Species:	Rattus norvegicus

Alignment Length:	320	Identity:	60/320 - (18%)
Similarity:	122/320 - (38%)	Gaps:	82/320 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   714 YEIFDIYNVLIGLDSKVIKMSAELNATNMFLKSFEMLFDTLSLNNLSFTQIDNGEEHLNDFNSET 778
            |..||:.::                 ...|.|..:...::..:.||....: |.|.||.:.:.||
  Rat    70 YNTFDLSDI-----------------AQCFTKCGQSDTNSCEVGNLQRYWL-NYESHLLENSMET 116

  Fly   779 IDYDDI-----GVSVYVSKYILYFSIIPSIANVSGIALFANNNKKNTPTKLKGAFKNEHYRFLQV 838
            :|...:     .:|..||:.:|| |::||                                  |:
  Rat   117 VDMPFVKALIQNISTDVSEDLLY-SLVPS----------------------------------QI 146

  Fly   839 NHNINDVVNEPDLELAAYLPIELIDTLQASTNKTNDVIVVI-----KVYSNDELFQ---QSVRNL 895
            ...:....::|...:.  ||..|...|..:.:.....|.::     .|:....|.:   .||.|
  Rat   147 PRQVMRGEDQPADRVR--LPKSLFGALPGNRSAVRLAITILNIGPGNVFKGPRLLEDKGSSVLN- 208

  Fly   896 TLLSRVVSISL-PGYSSFLPVPVPLIFRKSKNKKVNPPGSCLVWNY-EGWIDGYSMLSYFENNEG 958
               :|:|.:|: ..:::.|..||.:.| ..:::..|...:|:.|:. :|..|.:...:  |..:|
  Rat   209 ---NRMVGLSVGQMHATGLSEPVEITF-SHQHQSPNVILTCVFWDMAKGDWDSHGCST--EPGDG 267

  Fly   959 IALCRLRRLAPTGYFLEKKISIENHIINHDLRMSNTKLNGNIIYVILLSCCILMFIGFLF 1018
            ..:||...|  |.:.|..:.:::........|:|..   |:.:.:|.|:..:::::.|.|
  Rat   268 RTVCRCDHL--TFFALLLRPTLDQATARTLTRISQA---GSAVSMIFLAFTMVLYVAFRF 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43968	NP_001262238.1	None
Adgrg3	XP_038954076.1	GPS	244..282	CDD:396408	10/41 (24%)
		7tm_GPCRs	292..551	CDD:421689	7/34 (21%)
		TM helix 1	294..319	CDD:410628	5/27 (19%)
		TM helix 2	333..355	CDD:410628
		TM helix 3	366..393	CDD:410628
		TM helix 4	406..426	CDD:410628
		TM helix 5	454..481	CDD:410628
		TM helix 6	495..522	CDD:410628
		TM helix 7	524..549	CDD:410628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810