Protein Alignment CG43968 and Adgrg7

DIOPT Version :10

• Sequence 1: NP_001262238.1
• Gene: CG43968 / 14462915
• FlyBaseID: FBgn0264699
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_766413.2
• Gene: Adgrg7 / 239853
• MGIID: 2441732
• Length: 785
• Species: Mus musculus
• Alignment Length: 582
• Identity: 118/582 - (20%)
• Similarity: 214/582 - (36%)
• Gaps: 187/582 - (32%)

  Fly   459 NFAYNLCDE-VTDKNLRKLIESVYGNNNLGNLLIYDVRIMNIEWIKNMCVVFWIHITATLKSTAS 522
            |::|:..|: |.:.|:  .|:||..::|.|..:::.|:    :...|..|...|.|..|......
Mouse   239 NYSYSQGDQTVVEPNI--AIQSVTRDDNSGPSVLFSVQ----KGSSNSLVSGRILINKTANGLNP 297

  Fly   523 TYHKEIAFVDNTPRIPKD--FVAFMKVKITLSNFFLNFIKNSTYLLRSTDYCFSELSFSNDGMHL 585
            ....|:..:.||....|.  |:.:...|:..|..|          ..::|  ||:...|
Mouse   298 DGQTELQILLNTGENRKSCGFMVYQNHKLFQSKTF----------TATSD--FSQKIIS------ 344

  Fly   586 WWTTTRIGEIAMTK--KLCIQKDGMP---------YTRLCLGDFVHGAYWKKL-----TQPVVCE 634
                ::|.|....:  |:.::....|         ::..|:       ||..|     ||.  |:
Mouse   345 ----SKINESEQQRQNKVSVEMVFNPTYDKRELRLHSYACV-------YWNFLINDWDTQG--CQ 396

  Fly   635 SPKNNTKVLH-------DLQVAKMFKSPPEKVLKYLK--DIIAN--SKNSIVPADIFLIYKIFQS 688
            ...|.|:.|.       :..|...||    |..||.|  ||::|  ...||....:.::::|..
Mouse   397 KTGNTTEFLRCNCSHTTNFAVLMSFK----KDYKYPKSLDILSNIGCALSIAGLALTILFQILT- 456

  Fly   689 VHEIHSSNSEFQQTTKDLTNWK-----------NAIYEIFDIYNVLIGLDSKVIKMS-AELNA-- 739
                       ::..|....|.           |.:: :|.|.|     .:|.:|.| :::|.
Mouse   457 -----------RKIRKTSVTWVLVSLCSSMLIFNLLF-VFGIEN-----SNKNLKTSDSDINVKP 504

  Fly   740 -TNMFLKSFEMLFDTLSLNNLSFTQIDNGEEHLNDFNSETIDYDDIGVS-VYV----------SK 792
             .|...:|     ||:...|.|.|.|   ...|:.|...|..::.:..: :|.          ..
Mouse   505 ENNKIPES-----DTIETPNPSCTAI---AALLHYFLLVTFTWNGLSATQLYFLLIRTMKPLPRH 561

  Fly   793 YILYFSI----IPSIANVSGI---ALFA-NNNKKNTPTKLKGAFKNEHYRFLQVNHNINDVVNEP 849
            :|::.|:    :|:|  :.|:   :::| :.||:.....    ::.|...:|.|..: ||....|
Mouse   562 FIIFISLVGWGVPAI--IVGVTIGSIYALSGNKRYWELD----YRQEEICWLAVPKD-NDYARSP 619

  Fly   850 DLELAAYLPIELIDTLQASTNKTNDVIVVIKV-YSNDELFQQSVRNLTLLSRVVSISLPGYSSFL 913
             |..:..:|:.:|    ..||.|..||:.:|| :.|::       |||...:|.|:.    ..|.
Mouse   620 -LLWSFIIPVTII----LITNITIFVIITVKVLWKNNQ-------NLTSTKKVSSLK----KVFS 668

  Fly   914 PVPVPLIFRKSKNKKVNPPGSCLVWNYEGWIDGYSML----------SY----FENNEGIAL 961
            .:.:.::|..:                  ||..|:||          ||    |...:|:.:
Mouse   669 TLSIAVVFGVT------------------WILAYAMLISNDDIRIVFSYIFCLFNTTQGLQI 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43968	NP_001262238.1	None
Adgrg7	NP_766413.2	GPS	378..418	CDD:460350	10/48 (21%)
		GPS. /evidence=ECO:0000255|PROSITE-ProRule:PRU00098	380..425		14/57 (25%)
		7tmB2_GPR128	428..727	CDD:320385	70/352 (20%)
		TM helix 1	430..455	CDD:320385	5/24 (21%)
		TM helix 2	465..487	CDD:320385	3/22 (14%)
		TM helix 3	523..550	CDD:320385	6/29 (21%)
		TM helix 4	563..583	CDD:320385	5/21 (24%)
		TM helix 5	617..647	CDD:320385	10/34 (29%)
		TM helix 6	661..688	CDD:320385	7/48 (15%)
		TM helix 7	695..720	CDD:320385	4/18 (22%)