Protein Alignment CG43968 and ADGRL3

DIOPT Version :9

• Sequence 1: NP_001262238.1
• Gene: CG43968 / 14462915
• FlyBaseID: FBgn0264699
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: XP_016863418.1
• Gene: ADGRL3 / 23284
• HGNCID: 20974
• Length: 1586
• Species: Homo sapiens
• Alignment Length: 1049
• Identity: 193/1049 - (18%)
• Similarity: 334/1049 - (31%)
• Gaps: 355/1049 - (33%)

  Fly   160 IRR--NDELMPYEVRLPGKSWRKEINRSLIHLQNNPNEHCLKHTINNQTPADFKS---------Q 213
            :||  :.|..|.|:|.||..         :.:..:.|.......|.:..||..::         :
Human    98 VRRELSCESYPIELRCPGTD---------VIMIESANYGRTDDKICDSDPAQMENIRCYLPDAYK 153

  Fly   214 IVSVDCNAFLNAVCIFKSELISNAGCPSGFGALVYQPAVCYGIDWNNTTYEPLDLKEYLKKRNWL 278
            |:|..||.......:...::..:. ||..:..|..|             ||.:..|  ::::.:|
Human   154 IMSQRCNNRTQCAVVAGPDVFPDP-CPGTYKYLEVQ-------------YECVPYK--VEQKVFL 202

  Fly   279 RRILAKYVLKKNRHEFFKIDFF--------IHHSTKMEYVIKMSLSEDFQIVSKGLKWIPTLSKQ 335
            ...|.|.|.:.  ...|:.|..        :..|.|:.|                :.|.|..:..
Human   203 CPGLLKGVYQS--EHLFESDHQSGAWCKDPLQASDKIYY----------------MPWTPYRTDT 249

  Fly   336 IVKSSSAVEMV-------LEIDHRSKGVRLVIYNRKYLWKNNNSYVGVKCFALLKYGTLKNVRLD 393
            :.:.||..:.:       .::.||..|...|:|:....:.              |..|...|:.|
Human   250 LTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFN--------------KERTRNIVKFD 300

  Fly   394 LIWENQEQSYSILKVNI--VSSYRTEYWCEGHSIFEFQLVSTRLFV----DVNRSIAPV-----F 447
            |....:.....|...|.  .|.||   | .|.|..:..:....|:|    :.|.....:     :
Human   301 LRTRIKSGEAIIANANYHDTSPYR---W-GGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPY 361

  Fly   448 VLR----WNVSC--INANFAYNLCDEVTDKNLRKLIESVY---GNNNLGNLLIYDVRIMNIEWIK 503
            .||    |:.:.  .:|:.|:.:|      .:..:::|||   .|...||.:.|   |.|.:..|
Human   362 TLRIEGTWDTAYDKRSASNAFMIC------GILYVVKSVYEDDDNEATGNKIDY---IYNTDQSK 417

  Fly   504 NMCV-----------------------VFW--IHIT------ATLKS-TASTYHKEIAFV----- 531
            :..|                       ..|  .|:.      ..|.| :...:|.:::::
Human   418 DSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGQAHHGQVSYISPPIH 482

  Fly   532 -DNTPRIP--KDF-------VAFMKVKITLSNFFLNFIKNSTYLL-----RSTDY---------- 571
             |:....|  ||.       :.......||....|:..:::|..:     |||..
Human   483 LDSELERPSVKDISTTGPLGMGSTTTSTTLRTTTLSPGRSTTPSVSGRRNRSTSTPSPAVEVLDD 547

  Fly   572 -------------CFSELSFSNDGMHLWWTTTRIGEIA----------MTKKLCIQKDGMPYTRL 613
                         ...|...:.:...:.|..||.|:||          ::..||:..||:
Human   548 MTTHLPSASSQIPALEESCEAVEAREIMWFKTRQGQIAKQPCPAGTIGVSTYLCLAPDGI----- 607

  Fly   614 CLGDFVHGAYWKKLTQPVV-CESPKNNTKVLHDLQVAKMFKSPPEKVLKYLKDIIANSKNSIVPA 677
                      |......:. |.||..|       .:.:..|| .|......:::...::|.:...
Human   608 ----------WDPQGPDLSNCSSPWVN-------HITQKLKS-GETAANIARELAEQTRNHLNAG 654

  Fly   678 DI-FLIYKIFQSVH--EIHSSN-------------SEFQQTTKDLTNWKNAIYEIFDIYNVL--I 724
            || :.:..:.|.|.  ::...|             ::.|:..:....:..|:.|  .:.|:|  .
Human   655 DITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVE--TVNNLLQPQ 717

  Fly   725 GLDS-KVIKMSAELNATNMFLKSFE----MLFDTLSLNNLSFTQIDNGEEHL----NDFNSETID 780
            .|:: :.:..|.:|.|..|.|.:.|    :|.|.|...::.....||.:..:    .:.|.|.:.
Human   718 ALNAWRDLTTSDQLRAATMLLHTVEESAFVLADNLLKTDIVRENTDNIKLEVARLSTEGNLEDLK 782

  Fly   781 YDDIGVSVYVSKYILYFSIIPSIANVSGIALFANNNKKNTPTKLKGAFKNEHYRFLQVNHNINDV 845
            :.:                  ::.:.|.|.|.||..|:|.        :|...|...|.:|
Human   783 FPE------------------NMGHGSTIQLSANTLKQNG--------RNGEIRVAFVLYN---- 817

  Fly   846 VNEPDLELAAYLPIE----LIDTLQASTNKTNDVIV---VIKVYSNDELFQQSVRNLTLLSRVVS 903
                  .|..||..|    .:.|...|||  :.|||   ||....|.| |...|
Human   818 ------NLGPYLSTENASMKLGTEALSTN--HSVIVNSPVITAAINKE-FSNKV----------- 862

  Fly   904 ISLPGYSSFLPVPVPLIFRKSKNKKVNPPGSCLVWNYEGWIDGYSMLSYFENNEGIALCRLRRLA 968
                    :|..||....:..|..:.|...:|..|:|    ...:|..|: :.:|   |||....
Human   863 --------YLADPVVFTVKHIKQSEENFNPNCSFWSY----SKRTMTGYW-STQG---CRLLTTN 911

  Fly   969 PTGYFLEKKISIENHIIN----------------HDLRMSNTKLNGNIIYVILLSCCILMFIGFL 1017
            .|    ....|. ||:.|                |||.:......|.::.::.|..||..|
Human   912 KT----HTTCSC-NHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTF---- 967

  Fly  1018 FCKCIFRRL 1026
               |.||.|
Human   968 ---CFFRGL 973

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810