DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43783 and Cpeb4

DIOPT Version :9

Sequence 1:	NP_001261606.1	Gene:	CG43783 / 14462845	FlyBaseID:	FBgn0264305	Length:	1248	Species:	Drosophila melanogaster
Sequence 2:	NP_080528.2	Gene:	Cpeb4 / 67579	MGIID:	1914829	Length:	729	Species:	Mus musculus

Alignment Length:	402	Identity:	82/402 - (20%)
Similarity:	121/402 - (30%)	Gaps:	139/402 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KANSATSSASGSNSN-----------LSG---STSASASAATSP-TSSGTAVGGILSGAPKSPPG 57
            ||......:|..|||           |:|   ..:.....:|.| |||.:::.|..:.:....|
Mouse   114 KAEENPGDSSSENSNGKEKLRIESPVLTGFDYQEATGLGTSTQPLTSSASSLTGFSNWSAAIAP- 177

  Fly    58 LGSSTPISVRFNANEESLDDILQSFHHSKHSPSGGASGGGDASPTSNLLGMKNNGLGLVVGNCDS 122
             .|||.|      ||::      ||.|....|  |||....|....|.....:.|.|      .|
Mouse   178 -SSSTII------NEDA------SFFHQGGVP--GASANNGALLFQNFPHHVSPGFG------GS 221

  Fly   123 LS------------------------------SSPSQPQMHAGSASLFGNDEVSLRNNFMQAGGF 157
            .|                              :||..|.....||:.  |....|.||..:.
Mouse   222 FSPQIGPLSQHHPHHPHFQHHHSQHQQQRRSPASPHPPPFTHRSAAF--NQLPHLANNLNKP--- 281

  Fly   158 FNRKRSGSIEGVSPTSSGPSIISTLSTASAAGGGGSSVGGAVAAGDSNS--SGGTWRL-----IK 215
                       .||.||..|...|.|::.:.||||....||....|...  :||...|     :|
Mouse   282 -----------PSPWSSYQSPSPTPSSSWSPGGGGYGGWGASQGRDHRRGLNGGITPLNSISPLK 335

  Fly   216 GKVTQTIEEIKSSKLPPTAAIPIIVADPPSTGWSNDPDSDTECL--------TVNTSISEELPLD 272
            ........:::....|.:|..|        ..|..|..:..:.:        |.:....|...:|
Mouse   336 KNFASNHIQLQKYARPSSAFAP--------KSWMEDSLNRADNIFPFPERPRTFDMHSLESSLID 392

  Fly   273 LEHKQN-------------SDSDV------------EAEL--LQHDSISLGSGDVPTVAATG--- 307
            :...:|             |||.:            ::.|  ::...:..|.||.|..:..|
Mouse   393 IMRAENDSIKGRLNYSYPGSDSSLLINARTYGRRRGQSSLFPMEDGFLDDGRGDQPLHSGLGSPH 457

  Fly   308 ---HSERSRLRR 316
               |....|:.|
Mouse   458 CFTHQNGERVER 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43783	NP_001261606.1	None
Cpeb4	NP_080528.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	20..50
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	78..133		6/18 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..324		26/127 (20%)
		RRM1_CPEB2_like	472..563	CDD:241168
		RNA-binding. /evidence=ECO:0000250\|UniProtKB:Q17RY0	541..543
		RRM2_CPEB2_like	580..660	CDD:241170
		CEBP_ZZ	655..716	CDD:374504
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0129
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900