Protein Alignment CG43783 and CPEB2

DIOPT Version :9

• Sequence 1: NP_001261606.1
• Gene: CG43783 / 14462845
• FlyBaseID: FBgn0264305
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: XP_005248192.2
• Gene: CPEB2 / 132864
• HGNCID: 21745
• Length: 1037
• Species: Homo sapiens
• Alignment Length: 874
• Identity: 163/874 - (18%)
• Similarity: 262/874 - (29%)
• Gaps: 331/874 - (37%)

  Fly     5 KLPKANSATSSASGSNSNLSGSTSASASAAT----------SPTS--SGTAVGGILSGAPKSP-- 55
            |.|.|... |:|...|:.|:.||..:.:..:          ||::  .|.|:|.....:.:||
Human   284 KTPAAGEG-SAAESPNAGLASSTPVNPAPGSMESPNHPLLNSPSNLLPGGALGAGAFSSLQSPDL 347

  Fly    56 --PGLGSSTPISVRFNANEESLDDILQSFHHSKHSPSGGASGGGDASPTSNLLGMKNNGLGLVVG 118
              ||.|..                      .....|.||..|||.|||.. |.|.         |
Human   348 PHPGGGGG----------------------GGGGGPPGGGGGGGSASPPP-LPGF---------G 380

  Fly   119 NCDSLSSS----------PSQPQMH---------------AGSASLFGNDEVSLRNNFMQAGGFF 158
            ...|:.::          |:|||..               ..||:..|..          :||..
Human   381 TPWSVQTASPPPQPQQPPPTQPQQQPPPPQQPPQPQPQPPGSSATTPGGG----------SGGSL 435

  Fly   159 NR-------KRSGSIEGVSPTSSGPSIISTLSTAS----------AAGGGGSSVGGAVAAGDSNS 206
            :.       ..:|...|: |:|..|:...:.|..|          .:||||...||..:|
Human   436 SAMPPPSPDSENGFYPGL-PSSMNPAFFPSFSPVSPHGCTGLSVPTSGGGGGGFGGPFSA----- 494

  Fly   207 SGGTWRLIKGKVTQTIEEIKSSKLPPTAAIPIIVADPPSTGWSNDPDSDTECLTVNTSISEELPL 271
                               .:...||..|:.|....||.......|.|.      .:.:|.:  |
Human   495 -------------------TAVPPPPPPAMNIPQQQPPPPAAPQQPQSR------RSPVSPQ--L 532

  Fly   272 DLEH---------KQNSDSDVEAELLQ-----HDSISLGSGDVPTVAATGHSERSRLRRGLAHIR 322
            ..:|         ::||.:..:..|.|     |.|...|:|.:...|..|...|.....|:
Human   533 QQQHQAAAAAFLQQRNSYNHHQPLLKQSPWSNHQSSGWGTGSMSWGAMHGRDHRRTGNMGI---- 593

  Fly   323 SKVKAKQQAAPAMNKKDVSP-----SGSTVPATSVRTGFLRRRNVVEAGSEPSTSQQAEIAIASG 382
                     ...||:  :||     ||:.:....    |.|        |.||.:.::.|
Human   594 ---------PGTMNQ--ISPLKKPFSGNVIAPPK----FTR--------STPSLTPKSWI----- 630

  Fly   383 KVKKRGILLARKDVEIESGVEVLEDMIPSTAVHIDHSKDVANKRAEEVTDAGADADSRASLTLPV 447
                                   ||.:..|.   ::|..:...:...|         |:||.||
Human   631 -----------------------EDNVFRTD---NNSNTLLPLQVRMV---------RSSLQLP- 659

  Fly   448 APGFSTLASSYVEKESGVRDTRSRISFFSNLSMLSVSQ-----WREKH---QGATAFALPVLLSV 504
            |.|..:|..|:.......|..:.|...:.:|:|.|:..     .|.:|   :|..::..|...::
Human   660 AWGSDSLQDSWCTAAGTSRIDQDRSRMYDSLNMHSLENSLIDIMRAEHDPLKGRLSYPHPGTDNL 724

  Fly   505 LLI----------LLMILPVPDFLR--------GVFATLLFFTVMDCCGGHLRA-LLEDFMLTTH 550
            |::          ...:.|:.|.|.        ||..:      ..|...|... .:|.|
Human   725 LMLNARSYGRRRGRSSLFPIDDGLLDDGHSDQVGVLNS------PTCYSAHQNGERIERF----- 778

  Fly   551 PERVAF--AIPNYKFMPICEIPAVEEHKTIKTY-------AGWMNEINS---YDPNTFSFSLTR- 602
             .|..|  .:|          |.::|.:...::       ..|.::..|   :.|..::|.|.:
Human   779 -SRKVFVGGLP----------PDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQE 832

  Fly   603 --AVYVRLDGSI-----LKMSGTNARIPKR----RMWN----------EPPIDRHKIPFTDHRSY 646
              :|...:|..|     |.:..::..|..:    |.||          ..|:|..|..|......
Human   833 ESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPR 897

  Fly   647 DLRDCRIELL---------------------PLGLANKRFFNRKYPIQLIIKSNRDVPDEQSSVE 690
            .||...:.::                     |.|.....|.|::..|..|  |.|.|..:...::
Human   898 PLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAI--SARFVQLQHGDID 960

  Fly   691 SQSEAT--VKTD--AKEAKAASSSGTTPP 715
            .:.|..  |..|  ..|.:.|...|...|
Human   961 KRVEVKPYVLDDQMCDECQGARCGGKFAP 989

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43783	NP_001261606.1	None
CPEB2	XP_005248192.2	RRM	<767..942	CDD:223796	31/190 (16%)
		RRM1_CPEB2_like	780..871	CDD:241168	17/100 (17%)
		RRM2_CPEB2_like	888..968	CDD:241170	14/81 (17%)
		CEBP_ZZ	963..1024	CDD:292976	7/27 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0129
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900