Protein Alignment CG43777 and R3HDML

DIOPT Version :10

• Sequence 1: NP_001261163.1
• Gene: CG43777 / 14462631
• FlyBaseID: FBgn0264299
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_848586.1
• Gene: R3HDML / 140902
• HGNCID: 16249
• Length: 253
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 57/260 - (21%)
• Similarity: 77/260 - (29%)
• Gaps: 119/260 - (45%)

  Fly    52 KFHASVPNNMRMQKIALDILNNLRNKFAGGELRTKGNKTFAKARRMRQLFWDKELA--------- 107
            |.|.||    |.....||..|::|            ...:..|..|..:.|||.||
Human    55 KRHISV----RDMNALLDYHNHIR------------ASVYPPAANMEYMVWDKRLARAAEAWATQ 103

  Fly   108 ------------YMGNNHASTLSLKSSQCRSTLRFPHVGEAIALVTPREKLNLKEIYSKAFTPMF 160
                        |:|.|    ||:.|.|.||.                  ::|.:.:|:
Human   104 CIWAHGPSQLMRYVGQN----LSIHSGQYRSV------------------VDLMKSWSE------ 140

  Fly   161 AEYQHVSDPDALLHAFDPDRDFQ-----------VRHFTNIISDRVSRVGC------GVAVGAN- 207
             |..|        :.|...||..           ..|:|.::....:|:||      .::|..|
Human   141 -EKWH--------YLFPAPRDCNPHCPWRCDGPTCSHYTQMVWASSNRLGCAIHTCSSISVWGNT 196

  Fly   208 --------CNPSIKFCHFLTCYFDFHNMAGSYVYKAGDPTSSCDDWGVVSSDKYANLCKNSGEIF 264
                    ||.:||           .|..|...||.|.|.|||       ...|...| ||...|
Human   197 WHRAAYLVCNYAIK-----------GNWIGESPYKMGKPCSSC-------PPSYQGSC-NSNMCF 242

  Fly   265  264
            Human   243  242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43777	NP_001261163.1	CAP_euk	64..223	CDD:349399	38/205 (19%)
R3HDML	NP_848586.1	CAP_R3HDML	63..208	CDD:349409	36/193 (19%)