DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG43776 and CRISPLD2

DIOPT Version :9

Sequence 1:NP_001261162.1 Gene:CG43776 / 14462630 FlyBaseID:FBgn0264298 Length:270 Species:Drosophila melanogaster
Sequence 2:NP_113664.1 Gene:CRISPLD2 / 83716 HGNCID:25248 Length:497 Species:Homo sapiens


Alignment Length:293 Identity:65/293 - (22%)
Similarity:102/293 - (34%) Gaps:81/293 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 ILSAVLPV-ILMISTMTYGYNYCNNRTHRCILLNTQHFMCRLDKIPSLGGTRYHAIVPDIPKLRT 65
            :|..|:|: :|.:...:.||...|......:|...||         :...:|....:|...|  .
Human     4 VLGGVIPLGLLFLVCGSQGYLLPNVTLLEELLSKYQH---------NESHSRVRRAIPREDK--E 57

  Fly    66 EILRIINNFRNQFASGAFRTSENRTFTQAKRMRQILWDSELAYMARSHASTVSFQHTKCRSTVRF 130
            |||.:.|..|.|..            .||..|..:.||.||...|.:.||...::|   ..|...
Human    58 EILMLHNKLRGQVQ------------PQASNMEYMTWDDELEKSAAAWASQCIWEH---GPTSLL 107

  Fly   131 PRVGECLAMMVPKYKHTVHEALKKMFKIMFDEHLHIQDPRGLLQGFHPIRDY------------- 182
            ..:|:.|.....:|:               ....|:|      ..:..::||             
Human   108 VSIGQNLGAHWGRYR---------------SPGFHVQ------SWYDEVKDYTYPYPSECNPWCP 151

  Fly   183 ------VSSHFTIIVSDRVSRVGCGVAVGTNCRQGSS-----SNFCHFLTCYFDYDNVNGSYVYK 236
                  :.:|:|.||....:::||.|   ..||:.:.     .|..:|:..|....|..|...||
Human   152 ERCSGPMCTHYTQIVWATTNKIGCAV---NTCRKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYK 213

  Fly   237 AGKPASSC--SDWGTTKSKEFANLCYNNGNLIP 267
            .|:|.|.|  |..|:.::    ||||......|
Human   214 NGRPCSECPPSYGGSCRN----NLCYREETYTP 242

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43776NP_001261162.1 SCP_euk 64..225 CDD:240180 37/184 (20%)
CRISPLD2NP_113664.1 SCP_euk 56..201 CDD:240180 37/185 (20%)
LCCL 286..370 CDD:128866
LCCL 387..479 CDD:128866
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165151220
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2340
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1528782at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10334
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X35
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
65.850

Return to query results.
Submit another query.