DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43776 and CRISPLD1

DIOPT Version :9

Sequence 1:	NP_001261162.1	Gene:	CG43776 / 14462630	FlyBaseID:	FBgn0264298	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_113649.1	Gene:	CRISPLD1 / 83690	HGNCID:	18206	Length:	500	Species:	Homo sapiens

Alignment Length:	224	Identity:	55/224 - (24%)
Similarity:	82/224 - (36%)	Gaps:	69/224 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 ILRIINNFRNQFASGAFRTSENRTFTQAKRMRQILWDSELAYMARSHASTVSFQHTKCRSTVRFP 131
            ||.:.|..|:|            .:..|..|..:.||.||...|.|.|.:..::|....   ..|
Human    65 ILDLHNKLRSQ------------VYPTASNMEYMTWDVELERSAESWAESCLWEHGPAS---LLP 114

  Fly   132 RVGECLAMMVPKYK-HTVHEALKKMFKIMFDE-------HLHIQDPRGLLQGFHPIR--DYVSSH 186
            .:|:.|.....:|: .|.|      .:..:||       :.|..:|      :.|.|  ..|.:|
Human   115 SIGQNLGAHWGRYRPPTFH------VQSWYDEVKDFSYPYEHECNP------YCPFRCSGPVCTH 167

  Fly   187 FTIIVSDRVSRVGCGVAVGTNCRQGSSSNFCH-------------FLTC-YFDYDNVNGSYVYKA 237
            :|.:|....:|:||.:            |.||             :|.| |....|..|...||.
Human   168 YTQVVWATSNRIGCAI------------NLCHNMNIWGQIWPKAVYLVCNYSPKGNWWGHAPYKH 220

  Fly   238 GKPASSC--SDWGTTKSKEFANLCYNNGN 264
            |:|.|:|  |..|..:.    ||||..|:
Human   221 GRPCSACPPSFGGGCRE----NLCYKEGS 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43776	NP_001261162.1	SCP_euk	64..225	CDD:240180	40/181 (22%)
CRISPLD1	NP_113649.1	SCP_euk	63..207	CDD:240180	39/180 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	254..281
		LCCL	291..375	CDD:128866
		LCCL	392..483	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151157
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850