DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43776 and Crispld2

DIOPT Version :9

Sequence 1:	NP_001261162.1	Gene:	CG43776 / 14462630	FlyBaseID:	FBgn0264298	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001297564.1	Gene:	Crispld2 / 78892	MGIID:	1926142	Length:	495	Species:	Mus musculus

Alignment Length:	226	Identity:	49/226 - (21%)
Similarity:	75/226 - (33%)	Gaps:	76/226 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 RTEILRIINNFRNQFASGAFRTSENRTFTQAKRMRQILWDSELAYMARSHASTVSFQHTKC---R 125
            |.|||.:.|..|.|            .:..|..|..:.||.||...|.:.|....::|...   |
Mouse    56 RQEILMLHNKLRGQ------------VYPPASNMEHMTWDEELERSAAAWAHRCLWEHGPAGLLR 108

  Fly   126 STVRFPRVGECLAMMVPKYKHTVHEALKKMFKIMFDEHLHIQDPRGLLQGFHPIRDY-------- 182
            |      :|:.||:...:|:               ....|:|      ..:..::||
Mouse   109 S------IGQNLAVHWGRYR---------------SPGFHVQ------SWYDEVKDYTYPYPHEC 146

  Fly   183 -----------VSSHFTIIVSDRVSRVGCGVAVGTNCRQ----GSSSNFCHFLTC-YFDYDNVNG 231
                       :.:|:|.:|....:::||.|   ..||.    |.:.....:|.| |....|..|
Mouse   147 TPRCRERCSGPMCTHYTQMVWATTNKIGCAV---HTCRNMNVWGDTWENAVYLVCNYSPKGNWIG 208

  Fly   232 SYVYKAGKPASSCSDWGTTKSKEFANLCYNN 262
            ...||.|:|.|.|       ...:...|.||
Mouse   209 EAPYKHGRPCSEC-------PSSYGGGCLNN 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43776	NP_001261162.1	SCP_euk	64..225	CDD:240180	38/187 (20%)
Crispld2	NP_001297564.1	CAP	56..201	CDD:381818	37/186 (20%)
		LCCL	284..368	CDD:128866
		LCCL	387..486	CDD:367672
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841297
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.850