DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43776 and PI15

DIOPT Version :9

Sequence 1:	NP_001261162.1	Gene:	CG43776 / 14462630	FlyBaseID:	FBgn0264298	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001311332.1	Gene:	PI15 / 51050	HGNCID:	8946	Length:	258	Species:	Homo sapiens

Alignment Length:	222	Identity:	57/222 - (25%)
Similarity:	97/222 - (43%)	Gaps:	47/222 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 DIPKLR-------TEILRIINNFRNQFASGAFRTSENRTFTQAKRMRQILWDSELAYMARSHAST 116
            ||||.|       .:::.|: ::.||.        ..:.|..|..|..::||..||..|.:.|:|
Human    52 DIPKARRKRYISQNDMIAIL-DYHNQV--------RGKVFPPAANMEYMVWDENLAKSAEAWAAT 107

  Fly   117 VSFQHTKCRSTVRFPRVGECLAMMVPKYKHTVHEALKKMFKIMFDEHLHIQD----------PRG 171
            ..:.|.. ...:||  :|:.|::...:|:     ::.::.|..:||   ::|          ||.
Human   108 CIWDHGP-SYLLRF--LGQNLSVRTGRYR-----SILQLVKPWYDE---VKDYAFPYPQDCNPRC 161

  Fly   172 LLQGFHPIRDYVSSHFTIIVSDRVSRVGCGVAVGTNCR-QGSSSNFCHFLTC-YFDYDNVNGSYV 234
            .::.|.|    :.:|:|.:|....:|:||.:....|.. .||......:|.| |....|..|...
Human   162 PMRCFGP----MCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAP 222

  Fly   235 YKAGKPASSC-SDWGTTKSKEFANLCY 260
            ||.|.|.||| ..:|.:.:.   |||:
Human   223 YKVGVPCSSCPPSYGGSCTD---NLCF 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43776	NP_001261162.1	SCP_euk	64..225	CDD:240180	40/179 (22%)
PI15	NP_001311332.1	CAP_PI15	67..212	CDD:349408	38/168 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151199
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850