DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43776 and PI16

DIOPT Version :9

Sequence 1:NP_001261162.1 Gene:CG43776 / 14462630 FlyBaseID:FBgn0264298 Length:270 Species:Drosophila melanogaster
Sequence 2:NP_001186088.1 Gene:PI16 / 221476 HGNCID:21245 Length:463 Species:Homo sapiens


Alignment Length:224 Identity:53/224 - (23%)
Similarity:74/224 - (33%) Gaps:79/224 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    81 GAFRTSENRTFTQ------------AKRMRQILWDSELAYMARSHASTVSFQHTKCRSTVRFPRV 133
            ||....|.|...:            |..|..:.||.|||..|:::|....:.|.|.|.     |.
Human    26 GALTDEEKRLMVELHNLYRAQVSPTASDMLHMRWDEELAAFAKAYARQCVWGHNKERG-----RR 85

  Fly   134 GECLAMMVPKYKHTVHEALKKMFKIMFDEHLHIQDPRGLLQGFHPIRDY-----------VSSHF 187
            ||                  .:|.|. ||.:.:  |..:.:..|....|           :..|:
Human    86 GE------------------NLFAIT-DEGMDV--PLAMEEWHHEREHYNLSAATCSPGQMCGHY 129

  Fly   188 TIIVSDRVSRVGCGVAVGTNCRQGSSSNFC-----------HFLTC-YFDYDNVNGSYVYKAGKP 240
            |.:|..:..|:|||            |:||           ..|.| |....||.|...|:.|.|
Human   130 TQVVWAKTERIGCG------------SHFCEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEGTP 182

  Fly   241 ASSCSDWGTTKSKEFANLCYNNGNLIPAD 269
            .|.|......|:    :||...|:  |.|
Human   183 CSQCPSGYHCKN----SLCEPIGS--PED 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43776NP_001261162.1 SCP_euk 64..225 CDD:240180 39/178 (22%)
PI16NP_001186088.1 SCP_HrTT-1 33..166 CDD:240186 35/170 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 262..281
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 303..341
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 383..408
O-glycosylated at one site 386..395
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2340
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1528782at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10334
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X35
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
65.880

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