DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43776 and Crisp2

DIOPT Version :9

Sequence 1:	NP_001261162.1	Gene:	CG43776 / 14462630	FlyBaseID:	FBgn0264298	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001191000.1	Gene:	Crisp2 / 22024	MGIID:	98815	Length:	243	Species:	Mus musculus

Alignment Length:	214	Identity:	51/214 - (23%)
Similarity:	82/214 - (38%)	Gaps:	35/214 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 PDIPKLRT---EILRIINNFRNQFASGAFRTSENRTFTQAKRMRQILWDSELAYMARSHASTVSF 119
            ||...|.|   ::.|.|.|..|:     .|.|.|.|.:...:|.   |..:....|:..|:....
Mouse    25 PDFTSLLTNQLQVQREIVNKHNE-----LRRSVNPTGSDILKME---WSIQATTNAQKWANKCIL 81

  Fly   120 QHTKCRSTVRFPRVGECLAMMV-PKYKHTVHEALKKMFKIMFDEHLHIQDPRGLLQGFHPIRDYV 183
            :|:.........|.||.|.|.. |....||.::       .::|:      ...:.|.....:..
Mouse    82 EHSSKDDRKINIRCGENLYMSTDPTLWSTVIQS-------WYNEN------EDFVYGVGAKPNSA 133

  Fly   184 SSHFTIIVSDRVSRVGCGVAVGTNCRQGSSSNF--CHFLTCYFDYDNVNGSYVYKAGKPASS--- 243
            ..|:|.:|.....::|||:|...|  |.:...|  ||:  |....:.:..|..|:.|.|.:|
Mouse   134 VGHYTQLVWYSSFKIGCGIAYCPN--QDNLKYFYVCHY--CPMGNNVMKKSTPYQQGTPCASCPN 194

  Fly   244 -CSDWGTTKSKEFANLCYN 261
             |.:...|.|.:|.:|..|
Mouse   195 NCENGLCTNSCDFEDLLSN 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43776	NP_001261162.1	SCP_euk	64..225	CDD:240180	37/166 (22%)
Crisp2	NP_001191000.1	SCP_CRISP	36..171	CDD:240183	35/159 (22%)
Crisp2	NP_001191000.1	Crisp	189..243	CDD:285731	7/25 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841360
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750