DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43776 and vap-1

DIOPT Version :9

Sequence 1:	NP_001261162.1	Gene:	CG43776 / 14462630	FlyBaseID:	FBgn0264298	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001024553.1	Gene:	vap-1 / 181768	WormBaseID:	WBGene00006886	Length:	424	Species:	Caenorhabditis elegans

Alignment Length:	203	Identity:	47/203 - (23%)
Similarity:	86/203 - (42%)	Gaps:	31/203 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 KLRTEILRIINNFRNQFASGAFRTSENRTFTQAKRMRQILWDSELAYMARSHASTVSFQHTKCRS 126
            ||||.:.:.:.  .:..|:|||.       ..||:|.::.:...:...||:.|....:||:   :
Worm   245 KLRTSLAKGLE--ADGIAAGAFA-------PMAKQMPKLKYSCTVEANARTWAKGCLYQHS---T 297

  Fly   127 TVRFPRVGECLAMM----VPKYKHTVHEALKKMFKIMFDEHLHIQDPRGLLQGFHPIRDYVSSHF 187
            :.:.|.:||.|.|:    :||.: |..::.|..:..:.|  ..:.....|.|.   :.|....|:
Worm   298 SAQRPGLGENLYMISINNMPKIQ-TAEDSSKAWWSELKD--FGVGSDNILTQA---VFDRGVGHY 356

  Fly   188 TIIVSDRVSRVGCGVAVGTNCRQGSSSNFCHFLTCYFDYDNVNGSYVYKAGKPASSCSDWGTTKS 252
            |.:..:..:.:||.|   .||     ..|.:.:..|....|.....:|..|.|.::.:|...|::
Worm   357 TQMAWEGTTEIGCFV---ENC-----PTFTYSVCQYGPAGNYMNQLIYTKGSPCTADADCPGTQT 413

  Fly   253 KEFAN-LC 259
            ...|. ||
Worm   414 CSVAEALC 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43776	NP_001261162.1	SCP_euk	64..225	CDD:240180	36/164 (22%)
vap-1	NP_001024553.1	SCP	31..175	CDD:214553
vap-1	NP_001024553.1	SCP	234..386	CDD:214553	38/166 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020