DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43776 and vap-2

DIOPT Version :9

Sequence 1:	NP_001261162.1	Gene:	CG43776 / 14462630	FlyBaseID:	FBgn0264298	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001300377.1	Gene:	vap-2 / 181273	WormBaseID:	WBGene00011462	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	238	Identity:	61/238 - (25%)
Similarity:	99/238 - (41%)	Gaps:	44/238 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LDKIPSL----GGTRY--HAIVPDIPKLRTEILRIINNFRNQFASG-AFRTSENRTFTQAKRMRQ 99
            |.:.||:    ||:..  :::|.|:  .|...|...|.:|::.|.| .:....|.:..:|.:|.:
Worm   290 LCQAPSMVKDDGGSFQCDNSLVSDV--TRNFTLEQHNFYRSRLAKGFEWNGETNTSQPKASQMIK 352

  Fly   100 ILWDSELAYMARSHASTVSFQHTKCRSTVRFPRVGECLAMMV---PKYKHTVHEALKKM------ 155
            :.:|..|...|::.|:...|.|:   :....|..|:.|.|..   |..:..:|.|::|.
Worm   353 MEYDCMLERFAQNWANNCVFAHS---AHYERPNQGQNLYMSSFSNPDPRSLIHTAVEKWWQELEE 414

  Fly   156 FKIMFDEHL--HIQDPRGLLQGFHPIRDYVSSHFTIIVSDRVSRVGCGVAVGTNCRQGSSSNFCH 218
            |....|..|  .:.|.:|...|          |:|.:..||..|:|||:|   ||.: .|...||
Worm   415 FGTPIDNVLTPELWDLKGKAIG----------HYTQMAWDRTYRLGCGIA---NCPK-MSYVVCH 465

  Fly   219 FLTCYFDYDNVNGSYVYKAGKPASSCSDW--GTTKSKEFANLC 259
                |....|...:.:|:.|.|.....|.  ||...|. .:||
Worm   466 ----YGPAGNRKNNKIYEIGDPCEVDDDCPIGTDCEKT-TSLC 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43776	NP_001261162.1	SCP_euk	64..225	CDD:240180	44/172 (26%)
vap-2	NP_001300377.1	SCP	104..253	CDD:214553
vap-2	NP_001300377.1	SCP	315..468	CDD:214553	44/173 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920