DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43776 and GLIPR1L2

DIOPT Version :9

Sequence 1:	NP_001261162.1	Gene:	CG43776 / 14462630	FlyBaseID:	FBgn0264298	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001257325.1	Gene:	GLIPR1L2 / 144321	HGNCID:	28592	Length:	344	Species:	Homo sapiens

Alignment Length:	230	Identity:	51/230 - (22%)
Similarity:	79/230 - (34%)	Gaps:	56/230 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LGGTRYHAIVPDIPKLRTEILRIIN---NFRNQFASGAFRTSENRTFTQAKRMRQILWDSELAYM 109
            ||.:.....:||     .|.:..||   |..|:..........|        :|.:.||..|:..
Human    36 LGSSLNARFLPD-----EEDVDFINEYVNLHNELRGDVIPRGSN--------LRFMTWDVALSRT 87

  Fly   110 ARSHASTVSFQHTKCRSTV-----RFPRVGECLAMMVPKYKHTVHEAL------KKMFKIMFDEH 163
            ||:......|.|......|     :|..:||.: .:.|:.:.|...|:      |||:..
Human    88 ARAWGKKCLFTHNIYLQDVQMVHPKFYGIGENM-WVGPENEFTASIAIRSWHAEKKMYNF----- 146

  Fly   164 LHIQDPRGLLQGFHPIRDYVSSHFTIIVSDRVSRVGCGVAVGTNCRQ-GSSSNFCHFLTCYFDYD 227
                 ..|...|       ..|::..:|.|...:|||.|   |.|.: |...:...|:..|..
Human   147 -----ENGSCSG-------DCSNYIQLVWDHSYKVGCAV---TPCSKIGHIIHAAIFICNYAP-- 194

  Fly   228 NVNGSYVYKAGKPASSCSDWG-TTKSKEFANLCYN 261
              .|:...:..:|...|:..| ..|..:|  ||.|
Human   195 --GGTLTRRPYEPGIFCTRCGRRDKCTDF--LCSN 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43776	NP_001261162.1	SCP_euk	64..225	CDD:240180	38/175 (22%)
GLIPR1L2	NP_001257325.1	SCP_GLIPR-1_like	52..195	CDD:240185	37/175 (21%)
GLIPR1L2	NP_001257325.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..344
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151325
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750