DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG43776 and R3HDML

DIOPT Version :9

Sequence 1:NP_001261162.1 Gene:CG43776 / 14462630 FlyBaseID:FBgn0264298 Length:270 Species:Drosophila melanogaster
Sequence 2:NP_848586.1 Gene:R3HDML / 140902 HGNCID:16249 Length:253 Species:Homo sapiens


Alignment Length:229 Identity:51/229 - (22%)
Similarity:94/229 - (41%) Gaps:61/229 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 DIPKLRTE---ILRIIN---NFRNQFASGAFRTSENRTFTQAKRMRQILWDSELAYMARSHASTV 117
            ::|:.|.:   .:|.:|   ::.|...:..:..:.|        |..::||..||..|.:.|:..
Human    48 EVPRYRRKRHISVRDMNALLDYHNHIRASVYPPAAN--------MEYMVWDKRLARAAEAWATQC 104

  Fly   118 SFQHTKCRSTVRFPRVGECLAMMVPKYKHTVHEALKKMFKIMFDEHLHIQDPRGLLQGFHPIRDY 182
            .:.|...: .:|:  ||:.|::...:|:..|     .:.|...:|..|...|..        ||.
Human   105 IWAHGPSQ-LMRY--VGQNLSIHSGQYRSVV-----DLMKSWSEEKWHYLFPAP--------RDC 153

  Fly   183 -----------VSSHFTIIVSDRVSRVGCGVAVGTNCRQ----GSSSNFCHFLTCYFDYDNVNGS 232
                       ..||:|.:|....:|:||.:   ..|..    |::.:...:|.|.:   .:.|:
Human   154 NPHCPWRCDGPTCSHYTQMVWASSNRLGCAI---HTCSSISVWGNTWHRAAYLVCNY---AIKGN 212

  Fly   233 YV----YKAGKPASSC--SDWGTTKSKEFANLCY 260
            ::    ||.|||.|||  |..|:..|    |:|:
Human   213 WIGESPYKMGKPCSSCPPSYQGSCNS----NMCF 242

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43776NP_001261162.1 SCP_euk 64..225 CDD:240180 36/181 (20%)
R3HDMLNP_848586.1 SCP 65..207 CDD:320774 33/168 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165151178
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2340
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1528782at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10334
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X35
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
65.850

Return to query results.
Submit another query.