Protein Alignment CG43742 and LOC4578163

DIOPT Version :10

• Sequence 1: NP_001261130.1
• Gene: CG43742 / 14462622
• FlyBaseID: FBgn0263999
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_061512019.1
• Gene: LOC4578163 / 4578163
• VectorBaseID: AGAMI1_008809
• Length: 881
• Species: Anopheles gambiae
• Alignment Length: 577
• Identity: 123/577 - (21%)
• Similarity: 208/577 - (36%)
• Gaps: 197/577 - (34%)

  Fly    51 YNNSEFFCGGSLIHKQYVLTAAHCVRDLDE---VTVHLGENNRSCPIPVCKHVLRLNAKVILHPN 112
            |:.|...|.|.:|.:..|||.|.|..:..:   ..:::| |.|:   .|.||        ..||.
Mosquito   346 YSVSREDCYGLIIDEDTVLTLAQCTTNHGKRATFVMYMG-NERN---TVVKH--------YNHPG 398

  Fly   113 FHGNIFLNDIALLRLEREVIFEAHIRPICIILDED-------VTSNNQNNFTAYGWGKTEHGNIS 170
            :....:.|:|.||::....:|.....|.||..:.|       :|.:.:.:...:    :.|....
Mosquito   399 YREGQYYNNIGLLKVRTRFVFFRSFVPFCIWHENDLADSIVELTGHGRRDLNYF----SLHNASV 459

  Fly   171 DVL---SFIDLVR---LPKSMC------YQNINT------ICAGSTS---GDTCESDSGGPLIGN 214
            ||.   :|..:.|   ||.:.|      .:|::.      :|.|:.:   .:||:..:|||:.|.
Mosquito   460 DVFEPQNFQLIARANVLPINKCSYPEEFSKNLSNGLTDEHLCFGNEAYLVPETCQQAAGGPIGGK 524

  Fly   215 FVHRGKSRDILFGITSYGDAECS-GLFGVYTDVNAYKSWIASVVL---------------ESEPR 263
            .....|.....:.:.|:| .:|. |...|...::::..|:.||:|               |.|.
Mosquito   525 KFKFNKQFRYAYALNSFG-RDCGFGRAAVGVRLSSHIGWLQSVLLPDYRKDSGSVHFLHSELEE- 587

  Fly   264 LLNEYCKSDWGAK----------------------IF---------------------------- 278
              |:.|:...||:                      :|
Mosquito   588 --NDTCRHVDGAEGLCVEATRCPKIRYDFSVNRRVVFCQTSTVVCCPYENMVNKTTASGRELDEC 650

  Fly   279 ---LRLWEMSLFEHKF---------------------------AGALITNQFVVTVASALPDNFN 313
               ::....|..|.:|                           .|.|||::.|:|....|.....
Mosquito   651 AHRIKASSGSTNEAQFETGYIPEPYLVEVGWRGNGDAKAQWSCRGTLITSKAVLTSVKCLQQQSI 715

  Fly   314 A-SKIKVE-SKYLQVYDVDWALKHPHFEQAPRIRNNIALIRLAKMIPRSIFEI-PICLGLN---- 371
            | |.|::. ::...|.:|:..:.||.|:.... :||||||::...|.:|...| |.||..|
Mosquito   716 APSVIRLGLNEAAPVVNVEETILHPEFDVGSG-KNNIALIKMRDAIDQSTIAIYPACLWKNQTHT 779

  Fly   372 ------------FDS---PTTWNALLYSANNRFLGSQQVNLKRIHDCFEPNEYCVEKPDKLNYLP 421
                        .||   ||.    :|   ||       :.:.:.:....|:.||:      ..|
Mosquito   780 PFEMIQPVINGSTDSYVYPTA----MY---NR-------DCQALEEGLSSNQLCVD------VQP 824

  Fly   422 YDTPGS----VIGTSQMFKGREIYLIAGIISH-TQGD--VIVFTNIQDHVEWITTIM 471
            :||..|    :..:..|..|..:..:.||:|| |.||  |.|::.|..:|.||.:|:
Mosquito   825 HDTKVSLGDPLFWSEVMDDGTWVQYLVGIMSHVTAGDRTVHVYSRISSYVGWIKSIL 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43742	NP_001261130.1	Tryp_SPc	34..253	CDD:214473	51/233 (22%)
		Tryp_SPc	273..467	CDD:473915	61/302 (20%)
LOC4578163	XP_061512019.1	None