Protein Alignment CG43742 and LOC1278261

DIOPT Version :10

• Sequence 1: NP_001261130.1
• Gene: CG43742 / 14462622
• FlyBaseID: FBgn0263999
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_061514315.1
• Gene: LOC1278261 / 1278261
• VectorBaseID: AGAMI1_007870
• Length: 609
• Species: Anopheles gambiae
• Alignment Length: 611
• Identity: 152/611 - (24%)
• Similarity: 241/611 - (39%)
• Gaps: 193/611 - (31%)

  Fly     1 MCCWFSLLLVAVVIYQNAFAQ-LLD------------ENCKV-------------KITYRVAN-- 37
            ||...:.|.|.:.:...|..| .|:            ::|::             |:..||.|
Mosquito     1 MCKMLTHLTVVLTLASIALGQHFLEQPPINYSEGNSFDDCEIRFVTSYDQHESERKLHSRVTNIE 65

  Fly    38 ---------GHTAITSQF--MAAL-YNNS----EFFCGGSLIHKQYVLTAAHCVRDLDEV---TV 83
                     |..|...:|  |||: :..|    |:.||||||..::|||||||.:|::.:   ||
Mosquito    66 ISERIIAYGGERAYKGEFQHMAAIGWTRSETWIEYLCGGSLITWRFVLTAAHCSQDINYLPPDTV 130

  Fly    84 HLGENNRSC--------PIPVCKHVLRLNAKVILHPNFHGNIFLNDIALLRLEREVIFEAHIRPI 140
            .||:.:.:.        .||:        |:.|.||.:..:....|||::.||:.||..:.|...
Mosquito   131 RLGDTDLASTDDDETAQQIPI--------ARFIKHPQYRESRKYYDIAVVELEKNVIPNSAICVA 187

  Fly   141 CIILDEDVTSN--NQNNFTAYGWGKTEHGNISDVLSFIDLVRLPKSMCYQNINT----------- 192
            |:..:.:....  :...|.|.|:|:    .:|..|..:.|..|..::|.:.|.|
Mosquito   188 CVWRELEAPGELLDAVGFGALGFGE----KLSPSLQKVKLQALDATICAKRIPTNRRQMPEGLRD 248

  Fly   193 --ICAGSTSGDTCESDSGGP-------LIGNFVHRGKSRDILFGITSYGDAECSGLFGVYTDVNA 248
              :||.|.:.||||.|||||       |.||      :..::.|:.|:|.....|..||||.|::
Mosquito   249 DQLCAHSETMDTCEGDSGGPLQTDRHDLFGN------TFPLVVGVVSFGTPCTDGSTGVYTRVSS 307

  Fly   249 YKSWIASVVLESEPRLLNEYCKSDWGAKIFLR------------LW-EMSLFEHKFAGALITNQF 300
            |..||...|.:|   |..|.|.   |..:..|            || |.....::..|.||..||
Mosquito   308 YLDWIEKEVNQS---LSYEVCT---GVNVCDRKFNPSISPRVGLLWKETETDIYQCGGLLIDYQF 366

  Fly   301 VVTVASAL-----PDNFNAS-----KIKVESKYLQVYDVDWALKHPHF-EQAPRIRNNIALIRLA 354
            |:|.|..:     |..:.||     :..:|..::          ||.| :..|..  :||:|:|.
Mosquito   367 VITSADCVTSSKGPPTYVASSSDSDRAAIEEVFV----------HPRFIKGQPYF--DIAIIKLQ 419

  Fly   355 KMIPRSIFEI-PICLGLNFDSPTTWNALLYSANNRFLGSQQVNL------KRIHDCFEPNEYCVE 412
            |.  .::.|: |:||         |      :..|....:||||      .::....|.....|:
Mosquito   420 KY--ANLDELYPVCL---------W------SEERHGDWRQVNLLAGASVPQMRSYVEEFNISVK 467

  Fly   413 KPDKLNYLPYD-----------------TPGSVIGTSQMFKG------------REIYLIAGIIS 448
            ...:.:...||                 .|..|.|..::..|            .|.:.:.||:|
Mosquito   468 SSVQYDVDGYDCSVGENVAHNDLKCISNDPTLVPGLCEVDYGGPVLTDYYDIHYDEQFKVLGILS 532

  Fly   449 H-TQ--GDVIVFTNIQDHVEWITTIM 471
            . ||  |..::||::..|.:|:.:|:
Mosquito   533 RLTQGCGSEVIFTSLAPHRQWLESII 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43742	NP_001261130.1	Tryp_SPc	34..253	CDD:214473	80/269 (30%)
		Tryp_SPc	273..467	CDD:473915	54/256 (21%)
LOC1278261	XP_061514315.1	None