DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rgk1 and gem

DIOPT Version :9

Sequence 1:	NP_725875.3	Gene:	Rgk1 / 14462605	FlyBaseID:	FBgn0264753	Length:	1379	Species:	Drosophila melanogaster
Sequence 2:	NP_001039314.1	Gene:	gem / 560566	ZFINID:	ZDB-GENE-060825-251	Length:	291	Species:	Danio rerio

Alignment Length:	312	Identity:	93/312 - (29%)
Similarity:	147/312 - (47%)	Gaps:	58/312 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly  1034 VASMPNTGVEEEYYRLRHFSITGKGVVNRGDSLKSRRSRSNNSVASSNSSTEHLTTQQQLSAPAS 1098
            :||:....:..::: |..:||.|   .:.|..|.....||:.|::.|:|.:
Zfish     4 LASVRRHSIRVQHH-LHRWSICG---TDGGQLLNDAFPRSDISMSRSSSCS-------------- 50

  Fly  1099 VSARTSLASSRESSTSNPGN-GPYRVLMLGGPAVGKSSLVSQF------MTSEYLHAYDTSIDDE 1156
             ||.:..|.|.||:|  |.: ||:.|::||...||||:|.|.|      |.|| ...|...|.::
Zfish    51 -SASSDSALSTESAT--PASVGPFTVVLLGDNGVGKSALASIFAGASDSMGSE-CELYGGEIFEQ 111

  Fly  1157 S----GEKAVSVLLSGEESELIFIDHGYTEMTPDECLTNYDPHGYCVIYSAADRSSFSVAEQVLQ 1217
            :    ||:|...||...:|:    |.|  ..|...||...|  .:.::|:..|||||..|..:..
Zfish   112 TITVDGERASVTLLDTWDSQ----DEG--SWTQQRCLQTGD--AFIIVYAITDRSSFLRASDLRV 168

  Fly  1218 VLWTNQNIAQKAVILVSNKADLARSRLVTSEEGKAMATAYDCKFIETSVGINHNVDELLVGLLSQ 1282
            .|...:.:.:..:|||.||.||.|.|.|:..||::.|..:||||||||..:.|||..|..|::.|
Zfish   169 QLRREREVDRTPIILVGNKCDLVRCREVSISEGRSSAAVFDCKFIETSAAMQHNVWPLFEGIIRQ 233

  Fly  1283 IRLKLEN-----------------PEKSRDLFRKRSIRKSKRRACSPLNAGC 1317
            :||:.::                 |:|::....:...:|:|:.|....:..|
Zfish   234 LRLRRDSMETLSSHSSLQKRRESLPKKAKRFINRMVAKKNKQAAFKLKSKSC 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rgk1	NP_725875.3	DUF2967	459..715	CDD:288079
		P-loop_NTPase	1121..1379	CDD:304359	70/224 (31%)
		small_GTPase	1121..1286	CDD:197466	63/174 (36%)
gem	NP_001039314.1	RGK	71..291	CDD:206715	70/224 (31%)
gem	NP_001039314.1	small_GTPase	73..237	CDD:197466	63/172 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D301527at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45775
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020