DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rgk1 and rem1

DIOPT Version :9

Sequence 1:	NP_725875.3	Gene:	Rgk1 / 14462605	FlyBaseID:	FBgn0264753	Length:	1379	Species:	Drosophila melanogaster
Sequence 2:	NP_957468.1	Gene:	rem1 / 394149	ZFINID:	ZDB-GENE-040317-1	Length:	298	Species:	Danio rerio

Alignment Length:	335	Identity:	105/335 - (31%)
Similarity:	160/335 - (47%)	Gaps:	75/335 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  1070 RSRSNNSVASS--------NSSTE--HLTTQQQLS---APASVSARTSLASSRESSTSNPGNGPY 1121
            |.|::..:.||        :.||:  |....|..|   ...|:.:|.:.:|..||.:|. ....|
Zfish    14 RRRASTPIPSSRQAGRGDRDPSTDPYHPPLAQSASYHPGDKSIHSRANWSSDSESDSSG-SECLY 77

  Fly  1122 RVLMLGGPAVGKSSLVSQFMTSEYLHAYDTSIDDESGEKAVSVLLSGEESELIFIDHGYTEMTPD 1186
            ||::||...||||||.:.|...:...|: ..|.:::.|:  ::::.||::.|:.:|...|:...|
Zfish    78 RVVLLGDHGVGKSSLANIFAGIQEKDAH-KHIGEDAYER--TLMVDGEDTTLVVMDPWETDKQED 139

  Fly  1187 E--CLTNY---DPHGYCVIYSAADRSSFSVAEQV---LQVLWTNQNIAQKAVILVSNKADLARSR 1243
            :  .|.:|   ..:.|.::||..|||||..|.::   |:.:...:||   .:|||.||:||.|||
Zfish   140 DEKFLQDYCMQVGNAYIIVYSITDRSSFESASELRIQLRRIRQAENI---PIILVGNKSDLVRSR 201

  Fly  1244 LVTSEEGKAMATAYDCKFIETSVGINHNVDELLVGLLSQIRLKLENP---EKSRDLF-RKRSIRK 1304
            .|..|||:|.|..:||||||||..::|||.||..|.:.||||:.::.   |:.|.:: ||.||.|
Zfish   202 EVAVEEGRACAVMFDCKFIETSASLHHNVHELFEGTVRQIRLRRDSKEINERRRSVYKRKESITK 266

  Fly  1305 SKRRACSPLNAGCLNANTPLGPLGEAVATPPGSAQSSPRKYRGSRTSTSLKVKGLLGRVWTRDSK 1369
            ..||....|.|                               .:....:|||            :
Zfish   267 KARRFLDRLVA-------------------------------KNNKKMALKV------------R 288

  Fly  1370 SKSCENLHVL 1379
            ||||.:|.||
Zfish   289 SKSCHDLAVL 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rgk1	NP_725875.3	DUF2967	459..715	CDD:288079
		P-loop_NTPase	1121..1379	CDD:304359	88/269 (33%)
		small_GTPase	1121..1286	CDD:197466	68/172 (40%)
rem1	NP_957468.1	RGK	77..298	CDD:206715	88/269 (33%)
rem1	NP_957468.1	small_GTPase	77..244	CDD:197466	68/172 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D301527at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45775
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5084
SonicParanoid	1	1.000	-	-		X743
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.050