Protein Alignment Rgk1 and LOC1269547

DIOPT Version :10

• Sequence 1: NP_725875.3
• Gene: Rgk1 / 14462605
• FlyBaseID: FBgn0264753
• Length: 1379
• Species: Drosophila melanogaster
• Sequence 2: XP_061507930.1
• Gene: LOC1269547 / 1269547
• VectorBaseID: AGAMI1_008315
• Length: 1206
• Species: Anopheles gambiae
• Alignment Length: 1448
• Identity: 629/1448 - (43%)
• Similarity: 764/1448 - (52%)
• Gaps: 378/1448 - (26%)

  Fly    31 SPTPHPALAGPITSPPTSASSSSSTSTAADSTASSTINAPGAGPGGTATTRSRGARAMTASLAHA 95
            ||.|.||   |..|.|..........|.:.|.....|.:...||           .|.|..:|.|
Mosquito    38 SPPPIPA---PPPSTPRKNKVPPDAMTVSVSQPQQPIESVHCGP-----------LAATYIVASA 88

  Fly    96 AQGNHNNNSSTRSTSNSSSNTVKSKPPAGYMSTRSAAMMALALGQTSGGRSDKSPQAPRAASPAQ 160
            ..     .|||.|.|:||::      |...:...::..|||:                .|...|.
Mosquito    89 TP-----RSSTTSPSSSSAS------PTTVIDAVASPSMALS----------------SATMSAS 126

  Fly   161 SQSQSQSQSQSQSPHPGATRRLSNASSLPSNVSRSKPSTPTATRAAAQLNGSGLFSGGSNSSGSD 225
            |.|.|.|.::..||..|.           ::|:|..|...|.|.
Mosquito   127 SSSSSSSTARPTSPGHGR-----------ASVTRESPEPDTTTH--------------------- 159

  Fly   226 NDGFSASGSSAATALRRLYFKSGRSIKNKINASTTSSTPLNGLPLNPVSSAYHNSVGGPMHNMTT 290
                 .:.|:..:||||||||:.|:.|....|:|.::|      ...|::|           ..:
Mosquito   160 -----GNHSTPTSALRRLYFKTARASKAAKMAATAATT------ATAVAAA-----------AAS 202

  Fly   291 AGGVPKLVVMGTSSASIPDTTINTSTDSACTLITNVTHTDTSETCDSLDMGDNSCPSEPLFSSLE 355
            :..|||:||||:|:.|  :.|||||||||.|.:||||.|..:||.||||:||.|..||||.||||
Mosquito   203 SSTVPKVVVMGSSTTS--EATINTSTDSASTHVTNVTTTTDTETNDSLDLGDVSGQSEPLLSSLE 265

  Fly   356 EPLLTAVHI-----DSEHEGFGGMGGGRGGANGRGATELELTSCSRYPPRPDMNLQDSVESQESC 415
            :...:.:.:     :.|.|....:.|                        ||..|..|.:..|
Mosquito   266 DESSSIIALSQTAGNEEDENITVING------------------------PDTPLLISYQELE-- 304

  Fly   416 LSILTGEPSSTTPLLSSQRRHPTGGHSPGSQRQEERRERKEREPSTAP-PPTRIREHFTFDPPQS 479
                  :.|..:|:. |.|..|.  .:|||       ..:.::|.||| ..|..|  |.||||.|
Mosquito   305 ------DLSPRSPMF-SPRESPK--VTPGS-------NNRTQQPRTAPVSSTATR--FPFDPPMS 351

  Fly   480 PKSARSSEKSTSHFSFKNYGNESAKDAGVGSGKGTGSGAGVGGGGGSGSGVGGNGVMAASEGDEE 544
            ||                                |.||                ||   |.||..
Mosquito   352 PK--------------------------------TYSG----------------GV---SRGDIA 365

  Fly   545 DDERSGDSIGNRSKKLRPRERDPNHISPSVS------PSHSRRASPKREKRRTTPIASTGAISKV 603
            ...|:.:::.:..:...|..|.|..|.|:.|      |.||......     |.|...:.|..:|
Mosquito   366 SFARTHETMFSFDESPNPIRRPPPKIPPAPSSVEPDTPDHSPNIPID-----TAPGHESMAAREV 425

  Fly   604 SSAPPTMKDANFFGSSGKQKQRQSQNIP-------PHQLSPSSQQRKYSSSSSSGSSERCLREA- 660
            :..|               ||:|....|       |.:|..|.:.||......:||:......|
Mosquito   426 TQPP---------------KQQQLMEPPQTTTTSTPKRLMNSFKTRKERLVQQAGSAVAAATAAV 475

  Fly   661 TGPG----------------TMFPFDREALDYERIQRECFAPSS---------------TTASNS 694
            |..|                |||||||||:||:||||||||...               :.::.:
Mosquito   476 TSAGGTSGKPFKNPNYDPDLTMFPFDREAIDYDRIQRECFAVEEELLFEHDRRSDDDYRSVSAGA 540

  Fly   695 SDSEAENCSVYERKSGAD---IFQQYSRLSHQEQLQQHYQEPRDWERDRPPSRKNSKRIRPDSVI 756
            ...|:.:.:::|.:..:|   |||||:.|:.||            .||.||:.:|:
Mosquito   541 GGGESPSKALFEAEIFSDHYSIFQQYAYLTQQE------------TRDAPPAERNA--------- 584

  Fly   757 HTTIRENQQYVPQSDAFYPQAK-----------SSSSPSDHSYAELNKFEDIASKFEQIPPKHGS 810
             |..:.|:.....||||.||.:           ::|.|      .|:||:.||:||:.:|.|.||
Mosquito   585 -TPSKRNRMATTSSDAFSPQRRHLEHGSGVGSVAASQP------RLSKFDQIATKFDLMPSKTGS 642

  Fly   811 VSGS----GSGSLLNLH-----HKMPSPGSESAVSPTDSARRRSFKNKQRHQKEEHFY------I 860
            ...:    |.|:|.:|.     ......|:..:|||  |....:...|.|........      :
Mosquito   643 SVTAPQQLGCGTLPDLRVDYFAETSCCAGAGISVSP--SGESSTCDGKARASSPAATSGGGGGGL 705

  Fly   861 QTEDRSGTAA-GNGPINVTANPLEAAAVCKQPRATIVVQQPSLSLDNT-VETLLIKNEGDFISV- 922
            ::.:..||.| ..|.||||.||:| .|||.||||||||||||||||.| |||:|:|||||||||
Mosquito   706 RSMEVVGTGALAAGAINVTPNPME-GAVCTQPRATIVVQQPSLSLDYTSVETILLKNEGDFISVG 769

  Fly   923 EQGKELVARKRNSQQLAHPPAHLHHHTQNHAHNHHTLQQQQHQQQQQQQHKRDENMRQLLDVTNT 987
            |||                                |..:.|..|:::||  |:|:||||||||||
Mosquito   770 EQG--------------------------------TKGELQSTQRKKQQ--REEHMRQLLDVTNT 800

  Fly   988 LTIEELRDFQMRYGSPHHSRSQSVKMPGSRASGRPNQLCLPQQRSRVASMPNTGVEEEYYRLRHF 1052
            ||.||::||:|||||||||||||||.|||||||||||||||||||||||||||||||||||||||
Mosquito   801 LTTEEIKDFEMRYGSPHHSRSQSVKTPGSRASGRPNQLCLPQQRSRVASMPNTGVEEEYYRLRHF 865

  Fly  1053 SITGKGVVNRGDSLKSRRSRSNNSVASSNSSTEHLTTQQQLSAPASVSART----SLASSRESST 1113
            |||||||||||||||||||:||||||||||||||||  ....|.|:.||||    ||||||||||
Mosquito   866 SITGKGVVNRGDSLKSRRSKSNNSVASSNSSTEHLT--PAAGAVAAGSARTSATCSLASSRESST 928

  Fly  1114 SNPGNGPYRVLMLGGPAVGKSSLVSQFMTSEYLHAYDTSIDDESGEKAVSVLLSGEESELIFIDH 1178
            |||.:|||:|||||||||||||||||||||||||||||||||:||||.||||||||||||.||||
Mosquito   929 SNPASGPYKVLMLGGPAVGKSSLVSQFMTSEYLHAYDTSIDDDSGEKTVSVLLSGEESELTFIDH 993

  Fly  1179 GYTEMTPDECLTNYDPHGYCVIYSAADRSSFSVAEQVLQVLWTNQNIAQKAVILVSNKADLARSR 1243
            .|:||.|:.|::.|||||||||||:.|:.:|.:||::||:|||.:||||||||||:|||||||.|
Mosquito   994 SYSEMAPENCMSTYDPHGYCVIYSSTDKETFLIAERILQILWTTENIAQKAVILVANKADLARCR 1058

  Fly  1244 LVTSEEGKAMATAYDCKFIETSVGINHNVDELLVGLLSQIRLKLENPEKSRDLFRKRSIRKSKRR 1308
            :|||:|||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito  1059 VVTSDEGKAMATQYDCKFIETSVGINHNVDELLVGLLSQIRLKLENPEKSRDLFRKRSIRKSKRR 1123

  Fly  1309 ACSPLN--------AGCLNANTPL-GPL---GEAVATPPGSAQSSPRKYRGSRTSTSLKVKGLLG 1361
            |||||.        .|..|.:||: ||.   |..|.||||||.||||||||||||.|||||||||
Mosquito  1124 ACSPLGGAICLAGIGGSTNPSTPVSGPPASGGGFVDTPPGSAHSSPRKYRGSRTSASLKVKGLLG 1188

  Fly  1362 RVWTRDSKSKSCENLHVL 1379
            |||.||||||||||||||
Mosquito  1189 RVWARDSKSKSCENLHVL 1206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rgk1	NP_725875.3	DUF2967	16..899	CDD:402654	255/948 (27%)
		P-loop containing Nucleoside Triphosphate Hydrolases	1121..1379	CDD:476819	214/269 (80%)
LOC1269547	XP_061507930.1	None