DRSC/TRiP Functional Genomics Resources

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Protein Alignment koko and CCNK

DIOPT Version :10

Sequence 1:NP_732338.1 Gene:koko / 14462485 FlyBaseID:FBgn0264816 Length:259 Species:Drosophila melanogaster
Sequence 2:NP_001092872.1 Gene:CCNK / 8812 HGNCID:1596 Length:580 Species:Homo sapiens


Alignment Length:241 Identity:52/241 - (21%)
Similarity:112/241 - (46%) Gaps:25/241 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 NKAQTMKPIDYRKMNKPGVVPMYIFECAAKLKMKPLTAACAAIVFHRFFREVKASDYDEFLIAAG 81
            ::.:.:.|....:..:.|.  .:||:...:|.:...|.|...|.||||:.......:..::..|.
Human    36 SQLEGLDPATEARYRREGA--RFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGAC 98

  Fly    82 SLYLAGKIKEDESVKIRDVINVAYCTLNR------GNDPVDLNDEYWSMRDAIVQAELLITRTLC 140
            .|:||||::|... |.:|:|..|...||.      |:||          ::.::..|.::.:|:.
Human    99 CLFLAGKVEETPK-KCKDIIKTARSLLNDVQFGQFGDDP----------KEEVMVLERILLQTIK 152

  Fly   141 FDLNIDLAHKYLLHYMKTLQDWVGTEVWNSV-PIAKAAASYLQDFHHSANILKYKPTHVAIGCLS 204
            |||.::..:::||.|.|.|:   |.:  |.: .:.:.|.:::.|...:...|:::|..:|:..:.
Human   153 FDLQVEHPYQFLLKYAKQLK---GDK--NKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMY 212

  Fly   205 LALQTYGIQVPLTDESDESAMWYKPLVKDFTRENQWEIIENVIEVY 250
            ||.:....::...........|::..|:|...:...:|...::::|
Human   213 LAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLY 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kokoNP_732338.1 CYCLIN_CCNM_CCNQ_rpt1 32..142 CDD:410237 29/115 (25%)
CYCLIN_CCNM_CCNQ_rpt2 147..252 CDD:410238 19/105 (18%)
CCNKNP_001092872.1 CYCLIN_CCNK_rpt1 40..154 CDD:410233 30/126 (24%)
CYCLIN_CCNK_rpt2 158..258 CDD:410234 18/104 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 262..580
Blue background indicates that the domain is not in the aligned region.

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