Protein Alignment Polr2D and RPB4

DIOPT Version :10

• Sequence 1: NP_001014633.2
• Gene: Polr2D / 14462484
• FlyBaseID: FBgn0263757
• Length: 139
• Species: Drosophila melanogaster
• Sequence 2: NP_012395.1
• Gene: RPB4 / 853301
• SGDID: S000003676
• Length: 221
• Species: Saccharomyces cerevisiae
• Alignment Length: 200
• Identity: 48/200 - (24%)
• Similarity: 79/200 - (39%)
• Gaps: 73/200 - (36%)

  Fly    11 DEDAADLQFPKEF-----------ENAETLLISEVHMLL--------------------DHRKRQ 44
            :|:||.||..:||           |....|.:||..:::                    .|.|.:
Yeast    21 EENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKHKKKHLKHE 85

  Fly    45 N------------------------------ESADEEQEFSEVFMK------------TYAYTDS 67
            |                              |:.::|.|..:|.::            |..|..:
Yeast    86 NANDETTAVEDEDDDLDEDDVNADDDDFMHSETREKELESIDVLLEQTTGGNNKDLKNTMQYLTN 150

  Fly    68 FRKFKNKETIMSARSLLMQKKLHKFELAALGNLCPEAPEEAKALIPSLEGRFEDEELRQILDDIG 132
            |.:|:::||:.:...||....||.||:|.||:|..:..:|||.|||||..:..|:||.:||.::.
Yeast   151 FSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELS 215

  Fly   133 TKRSL 137
            ...:|
Yeast   216 NLETL 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr2D	NP_001014633.2	RPOL4c	22..139	CDD:128904	42/188 (22%)
RPB4	NP_012395.1	RPB4	15..221	CDD:227575	47/199 (24%)