Protein Alignment Rpb4 and POLR2D

DIOPT Version :9

• Sequence 1: NP_001014633.2
• Gene: Rpb4 / 14462484
• FlyBaseID: FBgn0263757
• Length: 139
• Species: Drosophila melanogaster
• Sequence 2: NP_004796.1
• Gene: POLR2D / 5433
• HGNCID: 9191
• Length: 142
• Species: Homo sapiens
• Alignment Length: 130
• Identity: 101/130 - (77%)
• Similarity: 112/130 - (86%)
• Gaps: 0/130 - (0%)

  Fly    10 VDEDAADLQFPKEFENAETLLISEVHMLLDHRKRQNESADEEQEFSEVFMKTYAYTDSFRKFKNK 74
            |:|||:.|.||||||.|||||.|||||||:|||:|||||::|||.|||||||..||..|.:|||:
Human    13 VEEDASQLIFPKEFETAETLLNSEVHMLLEHRKQQNESAEDEQELSEVFMKTLNYTARFSRFKNR 77

  Fly    75 ETIMSARSLLMQKKLHKFELAALGNLCPEAPEEAKALIPSLEGRFEDEELRQILDDIGTKRSLQY 139
            |||.|.||||:||||||||||.|.|||||..||:||||||||||||||||:||||||.||||.||
Human    78 ETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEGRFEDEELQQILDDIQTKRSFQY 142

  Fly   140  139
            Human   143  142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpb4	NP_001014633.2	RPOL4c	22..139	CDD:128904	91/116 (78%)
POLR2D	NP_004796.1	RPOL4c	24..141	CDD:128904	92/116 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156787
Domainoid	1	1.000	163	1.000	Domainoid score	I3979
eggNOG	1	0.900	-	-		E1_COG5250
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37968
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3777
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55689
OrthoDB	1	1.010	-	-		D1480091at2759
OrthoFinder	1	1.000	-	-		FOG0003764
OrthoInspector	1	1.000	-	-		oto89329
orthoMCL	1	0.900	-	-		OOG6_102742
Panther	1	1.100	-	-	LDO	PTHR21297
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1186
SonicParanoid	1	1.000	-	-		X4796
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800