Protein Alignment CG12256 and KLK4

DIOPT Version :10

• Sequence 1: NP_650166.2
• Gene: CG12256 / 14462452
• FlyBaseID: FBgn0038002
• Length: 283
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 73/250 - (29%)
• Similarity: 118/250 - (47%)
• Gaps: 39/250 - (15%)

  Fly    43 SQERVVGGYDV-PEDEYVPYQVSMQFLTRSGKMRHFCGGSLIAPNRVLTAAHCVNGQNASRISVV 106
            |..:::.|.|. |..:  |:|.:   |....::  ||.|.|:.|..||:||||.  ||:..|.:
Human    27 SCSQIINGEDCSPHSQ--PWQAA---LVMENEL--FCSGVLVHPQWVLSAAHCF--QNSYTIGL- 81

  Fly   107 AGIRDLNDSSGFRSQVQSYEMNENYQE----LVTSDIAILKIDPPFELDEKRVSTIDVSGSDMVG 167
             |:..|.......||:....::..:.|    |:.:|:.::|:|.... :...:.:|.:: |....
Human    82 -GLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVS-ESDTIRSISIA-SQCPT 143

  Fly   168 ADQEVLLTGWGSVFHFGTGPFAKYPTVLQKLDYKTLSNSKCKETMTQLTDTEI-CALERFG---- 227
            |....|::|||.:.:      .:.|||||.::...:|...|.:....|....: ||    |
Human   144 AGNSCLVSGWGLLAN------GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCA----GGGQD 198

  Fly   228 -KGACNGDSGGPLVMKSGESYKQVGVVSYGTAFCAS-NNPDVYTRVSMFDGWIKE 280
             |.:|||||||||:.   ..|.| |:||:|.|.|.. ..|.|||.:..|..||::
Human   199 QKDSCNGDSGGPLIC---NGYLQ-GLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12256	NP_650166.2	COG5640	44..282	CDD:444365	72/248 (29%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	72/245 (29%)