Protein Alignment CG12256 and Tmprss4

DIOPT Version :10

• Sequence 1: NP_650166.2
• Gene: CG12256 / 14462452
• FlyBaseID: FBgn0038002
• Length: 283
• Species: Drosophila melanogaster
• Sequence 2: NP_663378.1
• Gene: Tmprss4 / 214523
• MGIID: 2384877
• Length: 435
• Species: Mus musculus
• Alignment Length: 313
• Identity: 88/313 - (28%)
• Similarity: 138/313 - (44%)
• Gaps: 55/313 - (17%)

  Fly     7 FVLLLSSTLLALGGVQSKPMGNVIDL--DKYFEEADL--NSQE---------------------- 45
            |...|:.|.....|..|:|....:::  |:....|.:  ||||
Mouse   129 FTEALAKTACRQMGYDSQPAFRAVEIRPDQNLPVAQVTGNSQELQVQNGSRSCLSGSLVSLRCLD 193

  Fly    46 --------RVVGGYDVPEDEYVPYQVSMQFLTRSGKMRHFCGGSLIAPNRVLTAAHCVNGQ-NAS 101
                    |||||.:.|.|.: |:|||:|:     ..:|.||||::.|:.:||||||.... :.|
Mouse   194 CGKSLKTPRVVGGVEAPVDSW-PWQVSIQY-----NKQHVCGGSILDPHWILTAAHCFRKYLDVS 252

  Fly   102 RISVVAGIRDLNDSSGFR-SQVQSYEMNENYQELVTSDIAILKIDPPFELD-EKRVSTIDVSGSD 164
            ...|.||...|.:|.... :::...|.|..|.:  ..|||::|:..|.... ..|...:..|...
Mouse   253 SWKVRAGSNILGNSPSLPVAKIFIAEPNPLYPK--EKDIALVKLQMPLTFSGSVRPICLPFSDEV 315

  Fly   165 MVGADQEVLLTGWGSVFHFGTGPFAKYPTVLQKLDYKTLSNSKCKETMT---QLTDTEICA-LER 225
            :|.| ..|.:.|||.....|    .|...:|.:...:.:.:::|.....   ::|...:|| ..:
Mouse   316 LVPA-TPVWVIGWGFTEENG----GKMSDMLLQASVQVIDSTRCNAEDAYEGEVTAEMLCAGTPQ 375

  Fly   226 FGKGACNGDSGGPLVMKSGESYKQVGVVSYGTAFCASNNPDVYTRVSMFDGWI 278
            .||..|.|||||||:..| :.::.||:||:|......:.|.|||:|:.:..||
Mouse   376 GGKDTCQGDSGGPLMYHS-DKWQVVGIVSWGHGCGGPSTPGVYTKVTAYLNWI 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12256	NP_650166.2	COG5640	44..282	CDD:444365	78/272 (29%)
Tmprss4	NP_663378.1	LDLa	56..90	CDD:238060
		SRCR_2	106..195	CDD:470597	12/65 (18%)
		Tryp_SPc	202..427	CDD:214473	74/238 (31%)