DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12256 and PRSS21

DIOPT Version :9

Sequence 1:NP_650166.2 Gene:CG12256 / 14462452 FlyBaseID:FBgn0038002 Length:283 Species:Drosophila melanogaster
Sequence 2:NP_006790.1 Gene:PRSS21 / 10942 HGNCID:9485 Length:314 Species:Homo sapiens


Alignment Length:309 Identity:86/309 - (27%)
Similarity:129/309 - (41%) Gaps:66/309 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 LLSSTLLALGGVQSKPMGNVIDLDKYFEEADLNS-------QERVVGGYDVPEDEYVPYQVSMQF 67
            ||.:.|||..|:: ||...        |.|.|:.       ..|:|||.|.....: |:|.|::.
Human     7 LLLALLLARAGLR-KPESQ--------EAAPLSGPCGRRVITSRIVGGEDAELGRW-PWQGSLRL 61

  Fly    68 LTRSGKMRHFCGGSLIAPNRVLTAAHCVNGQNASRISVVAGIRDLNDSSGFRSQ----------- 121
            ..     .|.||.||::....||||||....:           ||:|.||:..|           
Human    62 WD-----SHVCGVSLLSHRWALTAAHCFETYS-----------DLSDPSGWMVQFGQLTSMPSFW 110

  Fly   122 -VQSY---------EMNENYQELVTSDIAILKIDPPFELDEKRVSTIDVSGSDMVGADQ-EVLLT 175
             :|:|         .::..|......|||::|:..|... .|.:..|.:..|.....:: :..:|
Human   111 SLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTY-TKHIQPICLQASTFEFENRTDCWVT 174

  Fly   176 GWGSVFHFGTGPFAKYPTVLQKLDYKTLSNSKCKETMTQLTDTE------ICA-LERFGKGACNG 233
            |||.:......|   .|..||::....::||.|.....:.:..:      :|| ..:.||.||.|
Human   175 GWGYIKEDEALP---SPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFG 236

  Fly   234 DSGGPLVMKSGESYKQVGVVSYGTAFCASNNPDVYTRVSMFDGWIKERM 282
            ||||||.......:.|:||||:|......|.|.|||.:|....||::.|
Human   237 DSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLM 285

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12256NP_650166.2 Tryp_SPc 46..278 CDD:214473 72/260 (28%)
Tryp_SPc 47..280 CDD:238113 73/261 (28%)
PRSS21NP_006790.1 Tryp_SPc 42..283 CDD:238113 73/261 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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