DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gas6 and drpr

DIOPT Version :9

Sequence 1:	NP_062394.2	Gene:	Gas6 / 14456	MGIID:	95660	Length:	674	Species:	Mus musculus
Sequence 2:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster

Alignment Length:	235	Identity:	64/235 - (27%)
Similarity:	84/235 - (35%)	Gaps:	84/235 - (35%)

- Green bases have known domain annotations that are detailed below.

Mouse   109 CVQNLPD-----QCTPN-PCDKKGTHICQDLMGNFFCVCTDGWGGRLCDKDVNEC-VQKNG-GCS 165
            |....||     ||..: ||...|.  ||...|  .|:|..||.|.:|   .|:| |...| ||.
  Fly   214 CDMRCPDGKHGAQCQQDCPCQNDGK--CQPETG--ACMCNPGWTGDVC---ANKCPVGSYGPGCQ 271

Mouse   166 Q--------VCHNKPGSFQCACHSGFSLASDGQTCQDIDEC-------TDSDTC---GDARCKNL 212
            :        .||:..|  ||.|..|:.    |:.|  .|||       ..|.||   .||.|...
  Fly   272 ESCECYKGAPCHHITG--QCECPPGYR----GERC--FDECQLNTYGFNCSMTCDCANDAMCDRA 328

Mouse   213 PGSYSCLCDEGYTYSS-KEKTCQ------------------------DVDECQ------QDRCEQ 246
            .|  :|:|:.|:|.:. .|:.|:                        :...||      ..:|.:
  Fly   329 NG--TCICNPGWTGAKCAERICEANKYGLDCNRTCECDMEHTDLCHPETGNCQCSIGWSSAQCTR 391

Mouse   247 TCV---NSPG-SYTCHCDGRGGLKLSPDMDTCEDILPCVP 282
            .|.   ..|. ..||:|  :.|.|.||...||    .|.|
  Fly   392 PCTFLRYGPNCELTCNC--KNGAKCSPVNGTC----LCAP 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gas6	NP_062394.2	GLA	26..90	CDD:214503
		EGF_CA	115..150	CDD:238011	14/40 (35%)
		FXa_inhibition	157..192	CDD:291342	13/44 (30%)
		EGF_CA	194..225	CDD:214542	13/40 (33%)
		cEGF	215..238	CDD:289433	6/47 (13%)
		FXa_inhibition	244..274	CDD:291342	10/33 (30%)
		LamG	295..447	CDD:238058
		Laminin_G_2	510..647	CDD:280389
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395	15/52 (29%)
		DSL	<479..518	CDD:302925
		DSL	<567..606	CDD:302925
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24035
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100