Protein Alignment TMEM120B and CG32795

DIOPT Version :10

• Sequence 1: NP_001074294.2
• Gene: TMEM120B / 144404
• HGNCID: 32008
• Length: 339
• Species: Homo sapiens
• Sequence 2: NP_570029.1
• Gene: CG32795 / 31270
• FlyBaseID: FBgn0040384
• Length: 387
• Species: Drosophila melanogaster
• Alignment Length: 333
• Identity: 156/333 - (46%)
• Similarity: 223/333 - (66%)
• Gaps: 2/333 - (0%)

Human     5 LERCEREWHELEGEFQELQETHRIYKQKLEELAALQTLCSSSISKQKKHLKDLKLTLQRCKRHAS 69
            ::..:.||.||..||.||:..:|.|.:.||:|.:.|.:|.:.|..|:..:..:..:|::.|....
  Fly     3 IDSLKNEWEELNKEFAELESCNRRYIELLEQLHSHQQICFNEIKHQRYRMNQITTSLRQFKGPVP 67

Human    70 REEAELVQQMAANIKERQDVFFDMEAYLPKKNGLYLNLVLGNVNVTLLSNQAKFAYKDEYEKFKL 134
            .|:.|.|..:.....:|:....::|..||.|:|.||.::||:|||::|:...|..|||:||||||
  Fly    68 AEDKEKVDDLHKMTLKRKAQLHEIEQSLPAKSGRYLQIILGDVNVSILNRNDKVRYKDDYEKFKL 132

Human   135 YLTIILLLGAVACRFVLHYRVTDEVFNFLLVWYYCTLTIRESILISNGSRIKGWWVSHHYVSTFL 199
            .|.:|.|:.|. ...:.:||..:..|.|||||||||||||||||..|||||||||.:||::||..
  Fly   133 ILNVIGLIMAF-FNLIFNYRALELAFIFLLVWYYCTLTIRESILKVNGSRIKGWWRAHHFISTVA 196

Human   200 SGVMLTWPNGPIYQKFRNQFLAFSIFQSCVQFLQYYYQRGCLYRLRALGERNHLDLTVEGFQSWM 264
            :||:|.||.|..:|.||.||:.|:::.|.||:||:.||:|.||||:|||||:::|:|:|||.|||
  Fly   197 AGVLLVWPQGEHWQIFRMQFMYFNVYISIVQYLQFGYQKGLLYRLKALGERHNMDITIEGFHSWM 261

Human   265 WRGLTFLLPFLFCGHFWQLYNAVTLFELSSHEECREWQVFVLAFTFLILFLGNFLTTLKVVHAKL 329
            ||||:|||||||.|:.:|.|||.||::|:.......|.|.|::..||:||:||..|||.||..|:
  Fly   262 WRGLSFLLPFLFIGYGYQAYNAWTLYKLAYSPPDAPWHVSVMSGLFLLLFVGNMATTLWVVPEKI 326

Human   330 QKNRGKTK 337
             :.|.|.:
  Fly   327 -RERAKER 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMEM120B	NP_001074294.2	TMPIT	9..332	CDD:462288	154/322 (48%)
CG32795	NP_570029.1	TMPIT	7..329	CDD:462288	154/323 (48%)