Protein Alignment Galr1 and AstA-R2

DIOPT Version :10

• Sequence 1: NP_032108.1
• Gene: Galr1 / 14427
• MGIID: 1096364
• Length: 348
• Species: Mus musculus
• Sequence 2: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Alignment Length: 314
• Identity: 112/314 - (35%)
• Similarity: 171/314 - (54%)
• Gaps: 17/314 - (5%)

Mouse    40 FGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLG 104
            ||:|...|..||.|||.|:..:  ...||||||.|:||:.|||.:::.||||.||.|.:..|..|
  Fly    45 FGVIAITGFFGNLLVILVVVFN--NNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYG 107

Mouse   105 AFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASP 169
            .|.|:.:.|...|:...||:||..||:||::|:||..||..:|.....|:.:..:|.:.:.::.|
  Fly   108 RFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVP 172

Mouse   170 VAY-HQRLFHRDS--NQTF--CWEQWPNKLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKK 229
            ||: |..:...|:  |.|:  |.....:.|..:.|.|..|:..|||||::|...|.:::..|.::
  Fly   173 VAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQ 237

Mouse   230 LK--NMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVVHLWAEFGAFPL-TPASFFFRITAHCLA 291
            ..  .|||:|:..:|:..:.|:|||:.|...|||..::.|......... |......::||..||
  Fly   238 GTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLA 302

Mouse   292 YSNSSVNPIIYAFLSENFRKAYKQVFKCHVCDESPRSETKENKSRMDTPPSTNC 345
            ||:|.:||::|||||||||||:.:...|       .|..:...|.:..|..|:|
  Fly   303 YSSSCINPLLYAFLSENFRKAFYKAVNC-------SSRYQNYTSDLPPPRKTSC 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galr1	NP_032108.1	7tmA_Gal1_R	34..313	CDD:320226	105/280 (38%)
		TM helix 1	35..61	CDD:320226	10/20 (50%)
		TM helix 2	70..96	CDD:320226	15/25 (60%)
		TM helix 3	108..138	CDD:320226	12/29 (41%)
		TM helix 4	150..170	CDD:320226	2/19 (11%)
		TM helix 5	196..225	CDD:320226	10/28 (36%)
		TM helix 6	239..269	CDD:320226	10/29 (34%)
		TM helix 7	281..306	CDD:320226	12/24 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..348		5/18 (28%)
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	105/280 (38%)
		TM helix 1	40..66	CDD:320224	10/20 (50%)
		TM helix 2	73..99	CDD:320224	15/25 (60%)
		TM helix 3	111..141	CDD:320224	12/29 (41%)
		TM helix 4	153..173	CDD:320224	2/19 (11%)
		TM helix 5	204..233	CDD:320224	10/28 (36%)
		TM helix 6	249..279	CDD:320224	10/29 (34%)
		TM helix 7	292..317	CDD:320224	12/24 (50%)