DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC2A14 and VVS1

DIOPT Version :10

Sequence 1:NP_001273166.1 Gene:SLC2A14 / 144195 HGNCID:18301 Length:535 Species:Homo sapiens
Sequence 2:NP_009800.1 Gene:VVS1 / 852543 SGDID:S000000445 Length:488 Species:Saccharomyces cerevisiae


Alignment Length:489 Identity:141/489 - (28%)
Similarity:226/489 - (46%) Gaps:49/489 - (10%)


- Green bases have known domain annotations that are detailed below.


Human    38 NGGVGEE---VTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLT 99
            |||..|.   :|..||....||.:||.|:||:...:|||:    ||::   ..:..||...:...
Yeast    10 NGGSRETKPLITGHLILGTIVACLGSIQYGYHIAELNAPQ----EFLS---CSRFEAPDENISYD 67

Human   100 NLW-----------------SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLM 147
            :.|                 ....:|||:||:.||:..|.:.||:||:...     :.|:..|::
Yeast    68 DTWVGQHGLKQCIALTDSQYGAITSIFSIGGLFGSYYAGNWANRYGRKYVS-----MGASAMCMV 127

Human   148 G--LCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQI 210
            .  |...:.|...|:.||.::|:.||......|::|.||:|...|||.|::||:.|.:|||:.|.
Yeast   128 SSLLLFFSNSYLQLLFGRFLVGMSCGTAIVITPLFINEIAPVEWRGAMGSMNQVSINLGILLTQT 192

Human   211 FGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGT-QDV 274
            ..|:........|.:..|..|  |:....|.....||||:|:.:....|..|.:.:...|| |..
Yeast   193 LALKYADSYNWRWLLFSGSVI--AVANILAWLKVDESPRWLVSHGFVSEAETALFKLRPGTYQQA 255

Human   275 SQDIQEM-------KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYST 332
            .|:||:.       :|..:........|:.:.....||::|..:.:.:...||..|||::.:|..
Yeast   256 KQEIQDWQRSHGHNRDPESSEETHSGPTLWQYVTDPSYKKPRTVILAILSCQQFCGINSIIFYGV 320

Human   333 GIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNH 397
            .:.........|....:..::|.:.||.:..:::..|||.|.:.....|...|.|::|.|.|   
Yeast   321 KVIGKILPDYSIQVNFAISILNVVVTLAASAIIDHVGRRPLLLASTTVMTAMSLLISVGLTL--- 382

Human   398 YNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSA 462
              .:||:.:.|..|::|.|.||.||||:.|:.||........|.:.....||.:.|:||.|||..
Yeast   383 --SVSFLLVTATFVYIAAFAIGLGPIPFLIIGELSYPQDAATAQSFGTVCNWLATFIVGYLFPIG 445

Human   463 AYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRT 496
            ...:|.|||.||......|..:.:.:||||:|:|
Yeast   446 HGLMGGYVFAIFAAIAAMFATYVYKRVPETKGKT 479

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC2A14NP_001273166.1 MFS_GLUT_Class1 51..495 CDD:340989 132/470 (28%)
VVS1NP_009800.1 MFS_GLUT_Class1_2_like 28..478 CDD:340915 132/468 (28%)

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