Protein Alignment SLC2A14 and ght3

DIOPT Version :10

• Sequence 1: NP_001273166.1
• Gene: SLC2A14 / 144195
• HGNCID: 18301
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_592790.1
• Gene: ght3 / 2541758
• PomBaseID: SPAC1F8.01
• Length: 555
• Species: Schizosaccharomyces pombe
• Alignment Length: 526
• Identity: 129/526 - (24%)
• Similarity: 218/526 - (41%)
• Gaps: 100/526 - (19%)

Human    45 VTPALIFAITVATIGSFQFGYNTGVINAPETII--KEFINKTLTDKANAPPSEVLLTNLW--SLS 105
            :|..|:..|:::  |..| |.:||.|:.   |:  ::|.:: ..|:.| |.|.....:.|  :|.
pombe     5 ITSILVVFISMS--GWLQ-GADTGSISG---ILGMRDFQSR-FADRYN-PISNSYSYSAWRQALL 61

Human   106 VAIFSVGGMIGSFSVGLFVNRFGRRNSM-------LIVNLLAATGGCLMGLCKIAESVEMLILGR 163
            ....:.|.:.|:.....|..|.|::.|:       :|..||..|.        :...:::|: |:
pombe    62 TGTINAGCLFGAMLSSPFTERIGKKYSICFFSGVYIIAELLLVTA--------VPSWIQVLV-GK 117

Human   164 LVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEEL-----W 223
            ::.|:..|..:...|.|..|::|..:|||.....|:......|||....    :|:.:|     |
pombe   118 ILAGVGIGALSVLSPGYQSEVAPPQIRGAVVATYQIFSTGAALVAACIN----MGTHKLRKTASW 178

Human   224 PVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQ--------- 279
            ....|..:|..||....:...|||||: ||.:.::|.|.||:..:......|:.||
pombe   179 RTSFGINMLWGILLMVGVLFLPESPRY-LIYKGRDEEALRIMCNMAELSPESEIIQTNFNTIKSD 242

Human   280 ---EMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ 341
               ||....||.        :|:|. ...|....:..::.|.::|.|.|..|||:|.:||..|:.
pombe   243 IEIEMAGGKARW--------IEIFG-KDIRYRTCLGFLVMLFRELIGNNYYFYYATQVFKGTGMT 298

Human   342 QPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTV----SLLLKN----HY 398
            ......:..|.:|...|..:|:.::..|||...:.|....:.|..:...    .|:.||    |.
pombe   299 DIFLPAVILGAINFGTTFGALYTIDNLGRRNPLIFGAAFQSICFFIYAAVGDRKLIYKNGTSDHR 363

Human   399 NGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFP--- 460
            .|...:....:.:|..|  ...||:.|.||.|.|....|....:||...||..||::....|
pombe   364 AGSVMIVFSCLFLFSYC--CSWGPMGWVIVGETFPIRYRSKCASVATSGNWLGNFMISFFTPFIN 426

Human   461 -SAAYYLGAYVFI---IFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVMG 521
             :..:.|| |::.   :|:.|:|.|||      .||:|.|.|::...:
pombe   427 NAIGFKLG-YIYACINLFSSFMIFFLA------KETKGLTLEEVNDLY----------------- 467

Human   522 MNSIEP 527
            |::|:|
pombe   468 MSNIKP 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A14	NP_001273166.1	MFS_GLUT_Class1	51..495	CDD:340989	121/486 (25%)
ght3	NP_592790.1	MFS_HXT	8..467	CDD:340914	125/498 (25%)