Protein Alignment SLC2A14 and ght2

DIOPT Version :10

• Sequence 1: NP_001273166.1
• Gene: SLC2A14 / 144195
• HGNCID: 18301
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_596425.1
• Gene: ght2 / 2539977
• PomBaseID: SPBC4B4.08
• Length: 531
• Species: Schizosaccharomyces pombe
• Alignment Length: 556
• Identity: 139/556 - (25%)
• Similarity: 236/556 - (42%)
• Gaps: 104/556 - (18%)

Human    42 GEEVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSV 106
            |:..|..::..:::|   .:.||.:||.|.. .|.:::| .:...|:.:.      :|:.:|||.
pombe     6 GKNFTLVMLIFVSMA---GWMFGADTGSIGG-VTSMRDF-RERYADRYDP------ITDQYSLSS 59

Human   107 A-------IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVE------M 158
            |       :.:||.:.|........:|||:|.|::        |.|.:.:..|...|.      .
pombe    60 ARQGLLTGMVNVGSLFGCIISSPIADRFGKRLSII--------GFCAVYIIGIIVQVTAVPSWVQ 116

Human   159 LILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEEL- 222
            :::.::..|:..|..:...|.|..|.:|.::||......||.:..||.:|....    :|:.:|
pombe   117 IMVAKIWTGIGIGALSVLAPGYQSETAPPSIRGTVVVTYQLFVTGGIFIAACIN----MGTHKLH 177

Human   223 ----WPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKD 283
                |.|.:|..:|..|:....:...|||||: ||...|:|.|.|:|..   :.::..|.:|:::
pombe   178 KTAQWRVSIGINLLWGIITMIGILFLPESPRY-LIQVGKDEEAVRVLSE---SAELFPDSEEVQN 238

Human   284 ESARMSQEKQVTVLELF---------------RVSSYRQPIIISIVLQLSQQLSGINAVFYYSTG 333
            |..|:..    ::.|.|               |..::....::|:     |||:|.|..|||...
pombe   239 EYHRLKS----SIDEEFAGGPCSWASIFGKDIRYRTFLGMFVMSL-----QQLTGNNYFFYYGFS 294

Human   334 IFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMT-VSLLLKNH 397
            :.:.||:..|..:.:....||...|...::::||.|||...:||....:.|..:.: |......|
pombe   295 VMQGAGINSPYLSAMILDAVNFGCTFGGMYVLERFGRRNPLIIGGIWQSICFFIYSAVGSRALYH 359

Human   398 YNGMSFVCIGAILVFVAC-----FEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGL 457
            .||.|....||:::.:||     |.....|..:.||.|.:....|....|||..|||..|||:..
pombe   360 KNGTSNTRAGAVMIVMACLFIFGFAQTWAPAAYVIVGESYPVRYRSKCAAVATASNWLWNFLISF 424

Human   458 LFPSAAYYLG---AYVFII--FTGFLITFLAFTFFKVPETRGRTFEDITRAF------------- 504
            ..|.....:|   .|||..  .||.::.||   |.|  ||:|.|.|:|...:
pombe   425 FTPFIQASIGFKYGYVFASCNLTGAIVIFL---FAK--ETKGLTLEEINELYMSVIKPWESGNFK 484

Human   505 ----EGQAHGADRSGKDGVMG--MNSIEPAKETTTN 534
                |.:....::|.|.|..|  :..:|.|..|.::
pombe   485 LNYSEQKKVEKEKSRKGGARGESVEYVERASNTDSS 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A14	NP_001273166.1	MFS_GLUT_Class1	51..495	CDD:340989	125/487 (26%)
ght2	NP_596425.1	MFS_HXT	12..471	CDD:340914	129/499 (26%)