Protein Alignment SLC2A14 and ght6

DIOPT Version :10

• Sequence 1: NP_001273166.1
• Gene: SLC2A14 / 144195
• HGNCID: 18301
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_587739.1
• Gene: ght6 / 2538845
• PomBaseID: SPCC1235.13
• Length: 535
• Species: Schizosaccharomyces pombe
• Alignment Length: 483
• Identity: 128/483 - (26%)
• Similarity: 213/483 - (44%)
• Gaps: 48/483 - (9%)

Human    50 IFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGM 114
            |..:...::..:.||.:||.|.. .|.:::|.:: ..|:.:.      :|:.:|.|.|  ..|.:
pombe     7 IVMLVFVSMAGWMFGADTGSIGG-ITNMRDFQSR-YADRYDP------VTDTYSYSSA--RQGLL 61

Human   115 IGSFSVGLFV---------NRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFC 170
            :|..:.|..|         :|||:|..::...|:..| |.::.|..|...|:|:: .::..||..
pombe    62 VGMVNTGTTVGCLLSSPLGDRFGKRKCIMGWTLVYIT-GVIVQLTTIPSWVQMMV-AKIWTGLGI 124

Human   171 GLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGL---ELILGSEELWPVLLGFTIL 232
            |..:...|.|..|.||..:|||..|..||.|.:||.:|....:   :.....|..|.|.:|..:|
pombe   125 GALSVIAPGYQSESSPPHIRGAIVTTYQLFITLGIFIAACINMGTHKYTTHPEAQWRVPIGINLL 189

Human   233 PAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVL 297
            ..||....:...|||||:|.:..:.|| ..:||.|..|   :..|...|:.|...:..:.:..:.
pombe   190 WGILMFFGMLFLPESPRYLAVKGRNEE-CMKILTRNAG---LPADHPIMQKEYNAIQADVEAELA 250

Human   298 -------ELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNT 355
                   ::|. :..|...::.:.:...|||:|.|..|||.|.:|:..|:..|..|.:....||.
pombe   251 GGPCSWPQIFS-NEIRYRTLLGMGVMAFQQLTGNNYFFYYGTQVFRGTGLNSPFLAALILDAVNF 314

Human   356 IFTLLSLFLVERAGRRTLHMIGLGGMAFCSTL-MTVSLLLKNHYNGMSFVCIGAILVFVACFEIG 419
            ..|..::|::|..|||...::|....:.|..: .:|........||.|....||:::..:|..|.
pombe   315 GCTFGAIFVLEYFGRRGPLIVGGVWQSICFFIYASVGDRALTRPNGTSNHRAGAVMIVFSCLFIF 379

Human   420 P-----GPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLG---AYVFIIFTG 476
            .     .|..:.||.|.:....|....|||..|||..||::....|..:..:|   .|||.. ..
pombe   380 SFAQTWAPAAYVIVGESYPIRYRSKCAAVATASNWFWNFMISFFTPFISNSIGFKYGYVFAA-CN 443

Human   477 FLITFLAFTFFKVPETRGRTFEDITRAF 504
            .....:.|.|.|  ||:|.|.|:|.:.:
pombe   444 LCAAIIIFLFAK--ETKGLTLEEINQLY 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A14	NP_001273166.1	MFS_GLUT_Class1	51..495	CDD:340989	123/471 (26%)
ght6	NP_587739.1	MFS_HXT	8..469	CDD:340914	127/480 (26%)