Protein Alignment Slc6a13 and GlyT

DIOPT Version :9

• Sequence 1: NP_001366036.1
• Gene: Slc6a13 / 14412
• MGIID: 95629
• Length: 602
• Species: Mus musculus
• Sequence 2: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Alignment Length: 621
• Identity: 251/621 - (40%)
• Similarity: 358/621 - (57%)
• Gaps: 78/621 - (12%)

Mouse     5 ASGTTSNGETKPVCPAMEKVEEDGTLEREHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGA 69
            |:|..:.|       |.|...|.||     |..:.:|:||:.|..:|||||||||||||.|||||
  Fly    42 ATGPGAGG-------AGESEHERGT-----WTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGA 94

Mouse    70 FFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIVSLLNVYYIVVLA 134
            |.||:.|.|...|:|:.|:|.:.|||...|.:..:||.||:|.|:|....::.:::.:||.:::|
  Fly    95 FLIPFTIMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIA 159

Mouse   135 WALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKAN--DSMN-----VTSENATS----------- 181
            |.:||:|:||...|||.:|...|:|:.|..:.:|:  ::.|     .|..||||
  Fly   160 WTIFYMFASFAPVLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLAL 224

Mouse   182 ------PVIEFWERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATF 240
                  |..|::...||.||.||:..||::..|..||.|||.|.:.|:.|||:|:||||||||.|
  Fly   225 GALKRPPAEEYFNNFVLGLSKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALF 289

Mouse   241 PYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNK 305
            ||::||:|.:||||||||:.||.|||.|:..:|.:.|||.||..||||:.:...|.|..|.||||
  Fly   290 PYVVLVILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNK 354

Mouse   306 YHNNCYRDCIALCILNSSTSFMAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLP 370
            :.||||:|.:.:...|.:|||.||..||||:||::.|..|.:.:|.:.|.|||||.||..|..||
  Fly   355 FSNNCYKDSLIVAFCNIATSFFAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLP 419

Mouse   371 FSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREV---LILIVSVISFFIGL 432
            .||:||..||.|::.|||||||..:|::.||::|.:|      |.|:.   ::|.|::..:..||
  Fly   420 VSPVWAVLFFVMLLTLGLDSQFALMETVTTAILDRFP------NLRQYKIWVVLSVAIFGYIGGL 478

Mouse   433 IMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAGRFYDNIEDMIGYKPWPLIKYCWL 497
            ...|..|||..||.|.|||:...|| :||.|.:.:||:||:.||.::|:.|||.:.|     .|.
  Fly   479 GFTTNSGMYWLQLMDKYAANWSVLL-IAISECILIAWIYGSQRFLNDIQGMIGKRSW-----FWN 537

Mouse   498 FF--------TPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMICI------PAW 548
            ||        |||..|....|:.::|.|..|. .|.||.|.||:||::.|..::.|      ..|
  Fly   538 FFWGIMWRYITPATLLFILFFNWVEYKPAKYG-HYVYPMWADAVGWIVGLLPVLVIFLVAFQEIW 601

Mouse   549 SIYKLRTLKGPL----RERLRQLVCPAEDLPQKNQP 580
                    :.|:    |:|::.|:.|..:.....:|
  Fly   602 --------RAPMSLSFRDRIKHLLQPTAEWGPAGRP 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc6a13	NP_001366036.1	SLC5-6-like_sbd	32..575	CDD:382020	242/587 (41%)
GlyT	NP_611836.2	SNF	57..603	CDD:249680	239/571 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	1	1.000	-	-		FOG0000575
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820