Protein Alignment Gabrg1 and Rdl

DIOPT Version :9

• Sequence 1: NP_034382.2
• Gene: Gabrg1 / 14405
• MGIID: 103156
• Length: 465
• Species: Mus musculus
• Sequence 2: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 541
• Identity: 156/541 - (28%)
• Similarity: 235/541 - (43%)
• Gaps: 138/541 - (25%)

Mouse    62 GD--ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
            ||  |:.||:|....||.::||:.|..|..:...:||.||..:..:.|::|:|..|.|.|.|.||
  Fly    55 GDVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRL 119

Mouse   125 KFNST--MKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAE 187
            .:...  ::.|.:.|..:..||:|||||.|.::|..|..||.|..:|:...|.:..::||||.|.
  Fly   120 AYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITAS 184

Mouse   188 CYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLR-NSTEISH 251
            |.:.|..||||...|.:|..|:||...:|.|.|:.....|.......|.||..:|.| .:|||:.
  Fly   185 CPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINL 249

Mouse   252 TISGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTL 316
            | :|:|..:.......|.|||:.||.|||..|.|::||||||:|::|.|||.:||:|||||||||
  Fly   250 T-TGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTL 313

Mouse   317 STIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNNKGKTTRGRKLK--------- 372
            .:....:|||:|||.::|:::..||:.|||:|:||.|:.|.....:.:..|...::
  Fly   314 MSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQ 378

Mouse   373 ----NKTSASP------------GLHAGSTLIPMNSISLPQG-----EDDYGY------------ 404
                |:..|:|            |:..|....|...:::..|     |..:|:
  Fly   379 LDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHA 443

Mouse   405 ----------------QCLEGKDCTSFFCCFDDCR----------TGSWREGRIH---------- 433
                            |.:..:.|:.....|.:.|          .|...|..::
  Fly   444 PKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHG 508

Mouse   434 ------------------------------------------------------IRIAKIDSYSR 444
                                                                  |..:.||.|||
  Fly   509 PGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSR 573

Mouse   445 IFFPTAFALFNLVYWVGYLYL 465
            |.||..|..|||:||:.||::
  Fly   574 IVFPVCFVCFNLMYWIIYLHV 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gabrg1	NP_034382.2	Neur_chan_LBD	65..270	CDD:280998	71/207 (34%)
		LIC	66..462	CDD:273305	151/530 (28%)
		Neur_chan_memb	277..459	CDD:280999	73/313 (23%)
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	61/183 (33%)
		Neur_chan_memb	274..588	CDD:397193	73/313 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910