Protein Alignment Gabrb3 and Rdl

DIOPT Version :9

• Sequence 1: NP_001033790.1
• Gene: Gabrb3 / 14402
• MGIID: 95621
• Length: 473
• Species: Mus musculus
• Sequence 2: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 587
• Identity: 192/587 - (32%)
• Similarity: 285/587 - (48%)
• Gaps: 135/587 - (22%)

Mouse     9 LLPIWLSWTLGTRGSEP---------------SSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGG 58
            ||.|||:..:.....|.               |.:.|. |:|.:   :|.....||.|:||::||
  Fly    20 LLTIWLAINMALIAQETGHKRIHTVQAATGGGSMLGDV-NISAI---LDSFSVSYDKRVRPNYGG 80

Mouse    59 PPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIP--LNLTLDNRVADQLWVPDT 121
            |||.||:.:.:.||..:|||.||:||..||:|:|.|.||||...|  ..|::.:.....:|||||
  Fly    81 PPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDT 145

Mouse   122 YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTT 186
            :|:|:|:|:.|..|..|..||:|..|::...:|:|.||:|.|:|:.:|:|.|.|.:||||:|||.
  Fly   146 FFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTM 210

Mouse   187 DDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTY 251
            .||.::||.|..:|.....:|||||.::.||..:..:...||.|.||:...:..|::||:::|.|
  Fly   211 RDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTGNYSRLACEIQFVRSMGYYLIQIY 275

Mouse   252 MPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVF 316
            :||.||.|:||||||:|.:|:.||||||:||||||||:.:.....||||.|||:||:||..|||.
  Fly   276 IPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVM 340

Mouse   317 VFLALLEYAFVNYIFFGRGPQRQK-----KLAEKTAKAKNDRSKSEIN----------------- 359
            ||.:|||||.|.|:......::|:     |:||:..:..:..::.:.|
  Fly   341 VFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGP 405

Mouse   360 ----------------------------RVDAHGN-------ILLAPMDVHNEMNEV-------- 381
                                        ...:||:       :...|:...|....|
  Fly   406 GGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIV 470

Mouse   382 ---------------AGSVGDTRNSAISFDNSGIQYRKQSMPKEGHGRYMG-------------- 417
                           |.|.|.|..:.::....|.|..... |.:|.|...|
  Fly   471 GPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPG-PGQGGGPPGGGGGGGGGGGPPEGG 534

Mouse   418 ---DRSIPHKKTHLRRRSSQLKIKIPDLTDVNA--------IDRWSRIVFPFTFSLFNLVYWLYY 471
               :.::|   .||.......|:|     |:|.        ||::||||||..|..|||:||:.|
  Fly   535 GDPEAAVP---AHLLHPGKVKKVK-----DINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIY 591

Mouse   472 VN 473
            ::
  Fly   592 LH 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gabrb3	NP_001033790.1	LIC	4..471	CDD:273305	191/583 (33%)
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	75/182 (41%)
		Neur_chan_memb	274..588	CDD:397193	90/322 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D226476at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101786
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720