Protein Alignment Gabra2 and Rdl

DIOPT Version :9

• Sequence 1: NP_032092.1
• Gene: Gabra2 / 14395
• MGIID: 95614
• Length: 451
• Species: Mus musculus
• Sequence 2: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 582
• Identity: 167/582 - (28%)
• Similarity: 245/582 - (42%)
• Gaps: 153/582 - (26%)

Mouse    16 VLLVWDPVRLVLANIQEDEAKNNITI--------------FTRILDRLLDGYDNRLRPGLGDSIT 66
            :|.:|..:.:.|. .||...|...|:              .:.|||.....||.|:||..|....
  Fly    20 LLTIWLAINMALI-AQETGHKRIHTVQAATGGGSMLGDVNISAILDSFSVSYDKRVRPNYGGPPV 83

Mouse    67 EVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKF-KGP-MNILRLNNLMASKIWTPDTFFH 129
            ||...:||.|...:|:..|::|:|.:|||.|.|.||.: |.| :..|.:.:.....||.|||||.
  Fly    84 EVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFV 148

Mouse   130 NGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEV 194
            |.|:|..|..|..|:.:|:...|::..::|||:.|.|||:|:.||||...|.::..|:.||..::
  Fly   149 NEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDI 213

Mouse   195 TYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYL 259
            .|.|....| ||.::.: ..|.|:.:||.......|..:||.|:.:.......|.:||::||.|:
  Fly   214 RYFWRDGLS-SVGMSSE-VELPQFRVLGHRQRATEINLTTGNYSRLACEIQFVRSMGYYLIQIYI 276

Mouse   260 PCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFV 324
            |..:.||:|.|||||||.:.|||...|||||||||||..|...:|||::|..::|.::..|:..|
  Fly   277 PSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMV 341

Mouse   325 FSALIEFATVNYFTK----RGWAWDGKSVVNDKKKEKGSVMIQNNAYAVAVAN------------ 373
            |::|:|:|||.|..|    |...:.....:.::||::.....|..|.....||
  Fly   342 FASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPG 406

Mouse   374 -----------------------------------YAP--NLSKDPV-LSTISKSATT------- 393
                                               :||  .:|..|: .|.|.::..|
  Fly   407 GPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVG 471

Mouse   394 -----------------------------------------------------------PEPNKK 399
                                                                       ||....
  Fly   472 PLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGD 536

Mouse   400 PEN-------KPAEAKKT--FNSV-----SKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
            ||.       .|.:.||.  .|.:     |.||:.|||||||.|..|||:||..||:...|:
  Fly   537 PEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVV 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gabra2	NP_032092.1	LIC	25..440	CDD:273305	162/564 (29%)
		LGIC_ECD_GABAAR_A2	47..249	CDD:349836	70/203 (34%)
		Cys-loop	166..180	CDD:349836	8/13 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..408		6/91 (7%)
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	63/184 (34%)
		Neur_chan_memb	274..588	CDD:397193	78/313 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010