Protein Alignment Gabpa and Ets97D

DIOPT Version :10

• Sequence 1: XP_006522968.1
• Gene: Gabpa / 14390
• MGIID: 95610
• Length: 456
• Species: Mus musculus
• Sequence 2: NP_001263000.1
• Gene: Ets97D / 43236
• FlyBaseID: FBgn0004510
• Length: 484
• Species: Drosophila melanogaster
• Alignment Length: 457
• Identity: 174/457 - (38%)
• Similarity: 251/457 - (54%)
• Gaps: 58/457 - (12%)

Mouse     6 AEELI-EIEIDGTEK----AECTEESI-VEQTYTPAECVSQAIDINEPIGNLKKLLEPRLQCSLD 64
            ::||| .:.:.|..:    :|..|:|| ||....|.:.:...:||.||:..||.|:|.::...|:
  Fly     8 SDELIRRLSVGGALEEVIASEMFEDSIDVETEAEPDDIIIVHMDIREPLSMLKSLVEQKIGVCLN 72

Mouse    65 AHEICLQDIQ-LDPDRSLFDQGVKTDGTVQLSVQVISYQGMEPKLNILEIVKTAETV------EV 122
            .:...|||.| |:..::|.||.||.:|.||::||:   |.:..::||.:::|..|..      ||
  Fly    73 YYTFWLQDAQELESHKNLVDQCVKGEGLVQINVQI---QTIRKRINIADVLKPTEAALAALAEEV 134

Mouse   123 VIDPDAHHAEAEAHLVEEAQVITLDGTKHITTISDETSE-----QVTRWAAALEGYRKEQERLGI 182
            |.........::.....|:.:.|.....|.....:|:.|     .|..|....: :::||.||.|
  Fly   135 VGQLSPPETASQKSSSSESPIKTPLKRMHKEDSEEESVEGKDVKPVLNWVLDSK-FKREQIRLKI 198

Mouse   183 PYDPIHWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPR--GEILWSHLE 245
            |.....|:...|.:|:.|.:|:|.:..|:::...::|:|||::..|:|.|::||  |.|.|:||:
  Fly   199 PEAANEWTHAHVTYWLEWAVKQFELVGINMSDWQMNGQELCAMTHEEFNQKLPRDPGNIFWTHLQ 263

Mouse   246 LLRKYVLAS------QEQQMNEIVTIDQPVQIIPASVPPATPTTIKVINSSAKAAKVQRSPRISG 304
            ||::....|      :||:        :|.|  |..:...:.:|    ||....:..||..|.|.
  Fly   264 LLKECNFVSVVHKRAEEQR--------KPKQ--PRIMSANSIST----NSGGSLSLEQRIMRKSY 314

Mouse   305 EDRSS------------PGNRTDL--GNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQP 355
            :...|            |.|.|.:  |||||:||||||||:|||.:..|.|.|||.||||||..|
  Fly   315 QSVKSSDSVESTTSSMNPSNYTTIGSGNNGQVQLWQFLLEILTDCEHTDVIEWVGTEGEFKLTDP 379

Mouse   356 ELVAQKWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLV 420
            :.||:.||::||||.|||||||||||||||||||.||.||||.|||.||||.||||.|.||:.||
  Fly   380 DRVARLWGEKKNKPAMNYEKLSRALRYYYDGDMISKVSGKRFAYKFDCDLKLLIGYDANELSTLV 444

Mouse   421 IE 422
            .|
  Fly   445 SE 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gabpa	XP_006522968.1	GABP-alpha	40..119	CDD:463311	28/79 (35%)
		SAM_PNT-GABP-alpha	168..254	CDD:176084	29/87 (33%)
		ETS	321..405	CDD:197710	61/83 (73%)
Ets97D	NP_001263000.1	GABP-alpha	48..123	CDD:463311	28/77 (36%)
		SAM_PNT-GABP-alpha	184..272	CDD:176084	29/88 (33%)
		ETS	345..429	CDD:197710	61/83 (73%)