DRSC/TRiP Functional Genomics Resources

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Protein Alignment POGLUT3 and CG31139

DIOPT Version :10

Sequence 1:NP_714916.3 Gene:POGLUT3 / 143888 HGNCID:28496 Length:507 Species:Homo sapiens
Sequence 2:NP_732797.1 Gene:CG31139 / 42698 FlyBaseID:FBgn0051139 Length:397 Species:Drosophila melanogaster


Alignment Length:398 Identity:106/398 - (26%)
Similarity:167/398 - (41%) Gaps:82/398 - (20%)


- Green bases have known domain annotations that are detailed below.


Human   122 DEHVAQS-------PYILKGPVYHEYCECPEDPQAWQKTLSCPTKEPQIAKDFASFPSINLQQML 179
            :||...|       |:||.....|..|.. .||:       |......|.:|...:....:...:
  Fly    30 NEHNPNSNTSYDFVPHILHALAIHRPCVI-GDPK-------CLCHVATIQRDLEPYVDKGITPEM 86

Human   180 KEVPKRFGDERGAIVHYTILNNHVYRRSLGKYTDFKMFSD--EILLSLTRKVLLPDLEFYVNLGD 242
            ....||.|      ..|.|:...:||:.  |....|..:|  ::||.:...|  .||||.:|:.|
  Fly    87 MAQSKRLG------TFYQIIRGRIYRQQ--KCLHPKRCADVEDLLLDMASGV--ADLEFVLNVRD 141

Human   243 WPLEHRKVNGTPSPIPIISWCGSLDSRDVVLPTYDITHSMLEAMRGVTNDLLSIQGNTGP----- 302
            ||..| .::|...|:                .:|.||:..|:.|    ....|....|||     
  Fly   142 WPQVH-FLSGLSGPV----------------FSYSITNRHLDIM----YPAWSFWTTTGPILQHY 185

Human   303 -------SWINK------------TERA--FFRGRDSREERLQLVQLSKENPQLLDAGITGYFFF 346
                   .|:.|            .:||  ||||..|..||..||:||:..|.|:||..|     
  Fly   186 PHGVGRWDWMRKHLVARASELPWSAKRAIGFFRGSRSSPERDSLVRLSQRRPDLVDAQYT----- 245

Human   347 QEKEKELGKAKLMGFFDFFKYKYQVNVDGTVAAYRYPYLMLGDSLVLKQDSPYYEHFYMALEPWK 411
             ....:....:.|...:..::||..|..|..|::|..:::|..||||.....:.|.||..|:||.
  Fly   246 -ILATDADPVEKMPLVEHCQFKYLFNFRGVAASFRLRHILLCRSLVLHVGDQWQEFFYSQLKPWV 309

Human   412 HYVPI--KRNLSDLLEKVKWAKENDEEAKKIAKEGQLMARDLLQPHRLYCYYYQVLQKYAERQSS 474
            ||||:  ..::.:|.|.:.:.:|:|:.|::||:.||......|:...:.||:.::||:||:..:.
  Fly   310 HYVPVASDADVDELAELILYLREHDDLAEEIAERGQQFIWLHLRMEDVQCYWSKMLQEYAKLLTY 374

Human   475 KPEVRDGM 482
            |.:...|:
  Fly   375 KVQREPGL 382

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
POGLUT3NP_714916.3 Filamin 24..134 6/18 (33%)
Filamin 27..131 CDD:395505 4/15 (27%)
Glyco_transf_90 151..485 CDD:329112 96/362 (27%)
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 504..507
CG31139NP_732797.1 Glyco_transf_90 61..397 CDD:310354 97/366 (27%)
Blue background indicates that the domain is not in the aligned region.

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