| Sequence 1: | NP_034376.1 | Gene: | Fzd9 / 14371 | MGIID: | 1313278 | Length: | 592 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001262037.1 | Gene: | fz2 / 40090 | FlyBaseID: | FBgn0016797 | Length: | 806 | Species: | Drosophila melanogaster |
| Alignment Length: | 615 | Identity: | 252/615 - (40%) |
|---|---|---|---|
| Similarity: | 341/615 - (55%) | Gaps: | 110/615 - (17%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 17 LATGGAALEIGRFDPERGRGPAP--------------CQAMEIPMCRGIGYNLTRMPNLLGHTSQ 67
Mouse 68 GEAAAQLAEFSPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNF 132
Mouse 133 GWPDSLDCARLPTRNDPHALCMEAP---ENATAGPTEPHKGLGMLPVAPRPARPPGDSAPGPGSG 194
Mouse 195 GT----------------CDNP--EKFQYVEKSRSC----------------------------- 212
Mouse 213 ----------APRCG-PGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVFTFLLEPHRFQYPER 266
Mouse 267 PIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGLENTG---CTLVFLLLYYFGMAS 328
Mouse 329 SLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVVLTLRKVAGDELTGLCYVAS 393
Mouse 394 MDPAALTGFVLVPLSCYLVLGTSFLLTGFVALFHIRKIMKT-----GGTNTEKLEKLMVKIGVFS 453
Mouse 454 ILYTVPATCVIVCYVYERLNMDFWRLRATEQPCTAATVPGGRRDCSLPGGSVPTVAVFMLKIFMS 518
Mouse 519 LVVGITSGVWVWSSKTFQTWQSLCYRKMAA 548 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Fzd9 | NP_034376.1 | CRD_FZ9 | 36..162 | CDD:143572 | 63/142 (44%) |
| Required for Wnt-activated receptor activity. /evidence=ECO:0000250|UniProtKB:Q8K4C8 | 59..173 | 50/116 (43%) | |||
| 7tmF_FZD9 | 222..543 | CDD:320164 | 163/328 (50%) | ||
| TM helix 1 | 231..256 | CDD:320164 | 14/24 (58%) | ||
| TM helix 2 | 265..286 | CDD:320164 | 10/20 (50%) | ||
| TM helix 3 | 315..341 | CDD:320164 | 19/25 (76%) | ||
| TM helix 4 | 358..374 | CDD:320164 | 7/15 (47%) | ||
| TM helix 5 | 396..426 | CDD:320164 | 17/29 (59%) | ||
| TM helix 6 | 445..472 | CDD:320164 | 19/26 (73%) | ||
| TM helix 7 | 504..529 | CDD:320164 | 15/24 (63%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 533..538 | 2/4 (50%) | |||
| Required for CTNNB1 accumulation and TCF transcription factor activity. /evidence=ECO:0000250|UniProtKB:Q8K4C8 | 555..592 | ||||
| fz2 | NP_001262037.1 | CRD_FZ5_like | 63..182 | CDD:143565 | 58/118 (49%) |
| Frizzled | 308..618 | CDD:279827 | 163/327 (50%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D237456at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X126 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 5 | 4.820 | |||||