Protein Alignment UBQLNL and DSK2

DIOPT Version :10

• Sequence 1: NP_659490.4
• Gene: UBQLNL / 143630
• HGNCID: 28294
• Length: 475
• Species: Homo sapiens
• Sequence 2: NP_014003.1
• Gene: DSK2 / 855319
• SGDID: S000004889
• Length: 373
• Species: Saccharomyces cerevisiae
• Alignment Length: 365
• Identity: 86/365 - (23%)
• Similarity: 136/365 - (37%)
• Gaps: 72/365 - (19%)

Human    35 VKTAGNQKDFMVADDISVRQFKEMLLAHFQCQMDQLVLVFMGCLLKDHDTLSQRGIMDGHTIYLV 99
            :|:..::.:..||.:.:|.||||.:.......:....|::.|.:|||..|:....|.|||:::||
Yeast     7 IKSGQDKWEVNVAPESTVLQFKEAINKANGIPVANQRLIYSGKILKDDQTVESYHIQDGHSVHLV 71

Human   100 IKSKQGSRSLAHSFRDLPTNDPCHRDRNTKGNSSRVHQPTGMNQ-APVELAHFVG------SD-- 155
            ....:...:.|....:............|...||  .|..|.|. |.:..|.:.|      :|
Yeast    72 KSQPKPQTASAAGANNATATGAAAGTGATPNMSS--GQSAGFNPLADLTSARYAGYLNMPSADMF 134

Human   156 APKVHTQNLEVSHPECKAQMLENPSIQ----RLLSN---MEFMWQFISEHLDTQQLMQQNPEVSR 213
            .|.....|.:.::.:...:|:|||..|    .:|||   ::||.|      ...||....|:..:
Yeast   135 GPDGGALNNDSNNQDELLRMMENPIFQSQMNEMLSNPQMLDFMIQ------SNPQLQAMGPQARQ 193

Human   214 LL--------LDNSEILLQTLELARNLAMIQEIMQIQQPSQNLEYPLNPQPYLGLET-----MPG 265
            :|        |.|.:::.|:::.||.:.....:......:.....|....|..|..|     ...
Yeast   194 MLQSPMFRQMLTNPDMIRQSMQFARMMDPNAGMGSAGGAASAFPAPGGDAPEEGSNTNTTSSSNT 258

Human   266 GNNALGQNYADINDQMLNSMQDPFGG------NPFT---------------ALLAGQVLEQVQSS 309
            |||| |.|..  .:...|:..:||..      |||.               ||||......||:|
Yeast   259 GNNA-GTNAG--TNAGANTAANPFASLLNPALNPFANAGNAASTGMPAFDPALLASMFQPPVQAS 320

Human   310 PPPP--PPSQEQQDQLTQHPATRVIYNSSG--GFSSNTSA 345
            ....  ||.:..:.||.|       .|..|  .|..|.:|
Yeast   321 QAEDTRPPEERYEHQLRQ-------LNDMGFFDFDRNVAA 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UBQLNL	NP_659490.4	Ubl_PLICs	29..101	CDD:340506	20/65 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	113..138		3/24 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..325		7/21 (33%)
DSK2	NP_014003.1	Ubl_Dsk2p_like	3..74	CDD:340523	20/66 (30%)
		STI1	149..185	CDD:128966	12/41 (29%)
		UBA_Dsk2p_like	328..369	CDD:270509	9/33 (27%)