DRSC/TRiP Functional Genomics Resources

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Protein Alignment UBQLNL and ubqln4

DIOPT Version :10

Sequence 1:NP_659490.4 Gene:UBQLNL / 143630 HGNCID:28294 Length:475 Species:Homo sapiens
Sequence 2:NP_998521.2 Gene:ubqln4 / 334337 ZFINID:ZDB-GENE-030131-6269 Length:599 Species:Danio rerio


Alignment Length:493 Identity:160/493 - (32%)
Similarity:240/493 - (48%) Gaps:97/493 - (19%)


- Green bases have known domain annotations that are detailed below.


Human    23 DKNISSSAT--RVIVKTAGNQKDFMVADDISVRQFKEMLLAHFQCQMDQLVLVFMGCLLKDHDTL 85
            ::|.::|||  :|.|||..::::..:|:|.||.||||.:...|:.:.|||||:|.|.:|||.|||
Zfish    16 EENAAASATIIKVTVKTPKDKEEIAIAEDASVAQFKEEISKRFKAKQDQLVLIFAGKILKDGDTL 80

Human    86 SQRGIMDGHTIYLVIKSKQ-----GSRSLAHSFRDLPT-NDPCHRDRNTKGNSSRVHQPTGMNQA 144
            .|.||.||.|::||||:.|     ||...:.|....|: ..|...|..:...:....|.:|.:..
Zfish    81 GQHGIKDGLTVHLVIKTAQKTSGAGSSQTSASSGPGPSQGSPSGTDTPSPAGNLGTPQGSGPSPT 145

Human   145 PVELAHFVGSDAPKVHTQNLE-----------------VSHPECKAQMLENPSIQRLLSNMEFMW 192
            |.:.|:.:..........||.                 :|:||..:|::|||.:|.::||.:.|.
Zfish   146 PSQPANILAGFGDLSGLSNLGMGSANFMELQQQMQRQLMSNPEMLSQIMENPLVQSMMSNPDLMR 210

Human   193 QFISEHLDTQQLMQQNPEVSRLLLDNSEILLQTLELARNLAMIQEIMQIQQPSQNLEYPLNPQPY 257
            |.|..:...||||::|||:|. :|:|.|::.||:|||||.||:||:|:.|..:.:          
Zfish   211 QMIMANPQMQQLMERNPEISH-MLNNPELMRQTMELARNPAMMQEMMRNQDRALS---------- 264

Human   258 LGLETMPGGNNALGQNYADINDQMLNSMQDPFGGNPFTALLAGQVLEQVQSSPPPPPPSQEQQDQ 322
             .||::|||.|||.:.|.||.:.|.::.::.||.|||:| |.|      ....|...||:.:..:
Zfish   265 -NLESIPGGYNALRRMYTDIQEPMFSAAREQFGNNPFSA-LGG------NGENPGTQPSRTENRE 321

Human   323 LTQHPATRVIYNSSGGFSSNTSANDTLNKVNHTSKANTAMISTKGQSHICATRQPAWI------- 380
            ...:|     :....|.:|.||:. |....:.|:.:.|..:|           .|..|       
Zfish   322 PLPNP-----WGPPDGTASTTSSG-TPTTTSSTTSSTTPSVS-----------NPLGISSSNLGN 369

Human   381 -----PALPSIELTQQLQEEYKDATVSLSSSRQTLKGDLQLSDEQSSSQITGGMMQLLMNNPYLA 440
                 |.:.|  |.||:.|                  :.||.....|:.....|||.|..||.:|
Zfish   370 GMFNSPGMQS--LMQQISE------------------NPQLMQNMISAPYMRTMMQSLAQNPDVA 414

Human   441 AQIM----LFTSMPQLSEQWRQQLPTFLQQTQISDLLS 474
            :|::    ||...|||.||.|||||.||||.|..:.||
Zfish   415 SQVLMNNPLFAGNPQLQEQMRQQLPVFLQQMQNPEALS 452

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UBQLNLNP_659490.4 Ubl_PLICs 29..101 CDD:340506 37/73 (51%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 113..138 3/25 (12%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 305..325 3/19 (16%)
ubqln4NP_998521.2 Ubl_PLICs 25..96 CDD:340506 34/70 (49%)
rad23 26..311 CDD:273167 106/303 (35%)
UBA_PLICs 556..595 CDD:270582
Blue background indicates that the domain is not in the aligned region.

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